Results 241 to 250 of about 36,653 (344)

Molecular Mechanisms, Endurance Athlete, and Synergistic Therapeutic Effects of Marine‐Derived Antioxidant Astaxanthin Supplementation and Exercise in Cancer, Metabolic Diseases, and Healthy Individuals

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
In metabolic disease, astaxanthin reduces lactate and carbohydrate (CHO) oxidation, while increasing fat oxidation, suggesting improved metabolic efficiency. In relation to exercise, astaxanthin enhances mitochondrial protection and biogenesis, boosts capillary blood flow, and improves oxygen delivery, all of which could lead to better endurance and ...
Wenwen Nie, Jianmin Li, Sogand Rajabi
wiley   +1 more source

Collective Total Synthesis of Four <i>Ganoderma</i> Meroterpenoids Based on an Intramolecular Aldol Strategy. [PDF]

Org Lett
Meguro Y, Oyake M, Enomoto M, Kuwahara S.   +3 more
europepmc   +1 more source

Efficacy of Haloxyfop‐R‐Methyl on Allium cepa: Cyto‐Genotoxic and In Silico Docking Studies on the Mechanism of Action

Microscopy Research and Technique, Volume 88, Issue 7, Page 2048-2062, July 2025.
ABSTRACT Haloxyfop‐R‐methyl (HRM) is extensively employed to control annual and perennial grass weeds. This study aimed to investigate the cyto‐genotoxic effects of HRM at concentrations of 1.19, 2.38, and 4.76 mg/L over various time intervals (24, 48, 72, and 96 h) on Allium cepa root.
Recep Liman, Emine Kılıç, Erman Salih İstifli, Yudum Yeltekin Uğur, İbrahim Hakkı Ciğerci   +4 more
wiley   +1 more source

Synthesis and resolution of a 1,1'-biazulene analogue of BINOL. [PDF]

RSC Adv
Gee AP, Gianga TM, Kociok-Köhn G, Pantoş GD, Lewis SE.   +4 more
europepmc   +1 more source

Delphinidin as an Antineoplastic Agent Targeting Androgen Receptors

ChemistrySelect, Volume 10, Issue 25, July 4, 2025.
Inhibition of Androgen Receptors by Capsicum chinense Delphinidin. Abstract Researchers globally have discovered that both red and green peppers are extremely rich in bioactive phytoconstituents with pharmacological properties. These metabolites are associated with critical physiological functions, including anticancer and health‐promoting effects ...
Leandro Miranda‐Alves, Sunday Amos Onikanni, Adewale Oluwaseun Fadaka, Tran Nhat‐Phong Dao, Nicole Remaliah Samantha Sibuyi, Omolola Esther Amos, Morenike Grace Ajayi, Ezekiel Adewole, Babatunji Emmanuel Oyinloye, Minh Hoang Le, Nguyen Thi Ai Nhung   +10 more
wiley   +1 more source

Engineering of the Thiamine Diphosphate-Dependent JanthE for the Synthesis of Tertiary Alcohols. [PDF]

Chemistry
Lanza L, Bjarnesen D, Çakar MM, Rizzo A, Pandya A, Aranda C, Blažević ZF, Müller M.   +7 more
europepmc   +1 more source

In Vitro and In Silico Evaluation of Isatin‐Derived Spirooxindoles as Antituberculosis Drug Candidates

Chemical Biology &Drug Design, Volume 106, Issue 1, July 2025.
Two compounds, A16 and A17, were active against multidrug‐resistant Mycobacterium tuberculosis isolates (PT‐12 and PT‐20), overcoming key resistance mutations in katG and rpoB, while cytotoxicity assays confirmed that they are non‐toxic. A17 exhibited the highest antituberculosis activity, with molecular docking suggesting enoyl‐[acyl‐carrier‐protein ...
Fernanda Rodrigues de Lima, Jéssika de Oliveira Viana, Aleff Cruz de Castro, Rodrigo Cristiano, Marcia Alberton Perelló, Alexia de Matos Czeczot, Cristiano Valim Bizarro, Pablo Machado, Luiz Augusto Basso, Claudio Gabriel Lima‐Junior, Valnês da Silva Rodrigues‐Junior, Karen Cacilda Weber   +11 more
wiley   +1 more source

Total Synthesis of (-)-Illisimonin A Enabled by Pattern Recognition and Olefin Transposition. [PDF]

J Am Chem Soc
Xu B, Zhang Z, Dai M.
europepmc   +1 more source

Functionalization, Fragmentation, and Expansion of cyclo‐P4R2 Ligands

Chemistry – A European Journal, Volume 31, Issue 36, June 26, 2025.
Three isolobal transition metal (TM) units are demonstrated to impact the transformation of coordinated P4 ligands in different ways. The observed reactivity primarily depends on the nature of the TM, an effect so far underexplored in phosphorus chemistry. This in‐depth analysis shines light on the underlying mechanistic principles and exploits them to
Christoph Riesinger, Lisa Zimmermann, Robert Szlosek, Gábor Balázs, Jan Wieneke, Lisa‐Marie Orel, Luis Dütsch, Manfred Scheer   +7 more
wiley   +1 more source

Stereoselective Total Synthesis of α-Galacto-Oligosaccharides Using Boron-Mediated Aglycon Delivery and Evaluation of their Immune-Enhancing Activities. [PDF]

Chembiochem
Meng J, Sagawa M, Toshima K, Takahashi D.   +3 more
europepmc   +1 more source