Results 151 to 160 of about 41,093 (226)

CMA‐mediated USP9X degradation promotes SHH medulloblastoma progression by facilitating SUFU ubiquitination

open access: yesClinical and Translational Medicine, Volume 16, Issue 3, March 2026.
Deubiquitinase USP9X suppresses SHH Medulloblastoma progression by facilitating SUFU ubiquitination. SHH promotes USP9X degradation through the CMA pathway. Combined inhibition of CMA and SHH pathway had a synergically therapeutic effect on SHH Medulloblastoma.
Binbin Gao   +12 more
wiley   +1 more source

The Regulation of Vasomotor and Cardiorespiratory Pulsations Is Disrupted in Primary Central Nervous System Lymphoma: A Case–Control fMRI Study

open access: yesHuman Brain Mapping, Volume 47, Issue 4, March 2026.
Using fast functional MRI, we assessed low‐frequency oscillations arising from cardiorespiratory pulsations and oscillatory interaction between respiratory and cardiac pulsations in primary central nervous system lymphoma. Respiratory‐related oscillations showed brain‐wide increases with a link to mortality whereas increases in cardiovascular‐related ...
Valter Poltojainen   +15 more
wiley   +1 more source

Anatomical Localization–Based Analysis of Relapsed Secondary Central Nervous System Aggressive B‐Cell Lymphoma (R‐SCNSL)

open access: yesHematological Oncology, Volume 44, Issue 2, March 2026.
ABSTRACT 162 patients with relapsed secondary central nervous system lymphoma (R‐SCNSL) (median age, 65 years; male, 59.9%) including central nervous system (CNS)‐only (n = 120) and concomitant CNS/systemic relapse (n = 42) were retrospectively analyzed.
Izel Okcu   +11 more
wiley   +1 more source

Successful Treatment of Paranasal Sinus Metastasis From Renal Cell Carcinoma With Immune Checkpoint Inhibitors and Radiotherapy: A Case Report

open access: yesIJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction Renal cell carcinoma (RCC) metastasis to the paranasal sinuses is rare and lacks standard treatment, particularly for unresectable tumors. We report a case of sphenoid sinus metastasis with sarcomatoid differentiation successfully managed with radiation therapy and immunotherapy.
Shota Yamada   +7 more
wiley   +1 more source

Magnetic Resonance Guided Radiation Therapy (MRgRT) Prostate Motion and Margins

open access: yesJournal of Medical Radiation Sciences, Volume 73, Issue 1, Page 44-51, March 2026.
This study evaluated intra‐fractional prostate motion during MR‐guided radiotherapy to determine appropriate PTV margins for prostate cancer. Analysis of 18 patients resulted in calculated margins of 3.2 mm (AP), 1.7 mm (LR), and 3.2 mm (SI), supporting the potential for margin reduction with MRgRT. ABSTRACT Introduction Systematic and random errors in
Sammi Peng   +7 more
wiley   +1 more source

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