Results 151 to 160 of about 52,263 (284)

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Clinical Utility of 68Ga‐DOTATOC Positron Emission Tomography/Computed Tomography in Evaluating Metastatic Lesions of Clear Cell Renal Cell Carcinoma: A Case Report

open access: yesIJU Case Reports, Volume 9, Issue 4, July 2026.
ABSTRACT Introduction 68Ga‐DOTATOC positron emission tomography/computed tomography (PET/CT) targets somatostatin receptors (SSTRs) and is an established molecular imaging modality for neuroendocrine tumors (NETs). Although SSTR expression has been reported in renal cell carcinoma (RCC), its clinical utility remains unclear. Case Presentation A 76‐year‐
Yuta Mine   +9 more
wiley   +1 more source

Malignant craniopharyngiomas: Institutional experience and literature review

open access: yesBrain Pathology, Volume 36, Issue 4, July 2026.
We report the second case of malignant craniopharyngioma with BAP1 and TP53 mutations. A literature review identified 44 cases of malignant craniopharyngiomas with a median overall survival of 6 months. Eighteen (41%) occurred in patients without any history of radiation, suggesting that mechanisms other than radiation have contributed to their ...
Thomas J. Auen   +10 more
wiley   +1 more source

Mucous Membrane Pemphigoid After Anti‐PD‐1 Therapy: Risk‐Stratified Management and Treatment Outcomes

open access: yesInternational Journal of Dermatology, Volume 65, Issue 7, Page 1376-1382, July 2026.
ABSTRACT Mucous membrane pemphigoid (MMP) following anti‐programmed cell death‐1 (PD‐1) therapy is rare but increasingly reported. Management of high‐ and low‐risk MMP in this setting and the potential oncologic trade‐offs remain poorly defined. We performed a narrative synthesis of all published cases of anti‐PD‐1‐associated MMP, following MEDLINE ...
Serena Dienes   +2 more
wiley   +1 more source

Executive summary of American Radium Society Appropriate Use Criteria for the treatment of locoregionally recurrent rectal cancer

open access: yesCancer, Volume 132, Issue 12, 15 June 2026.
Abstract This literature‐based systematic review and associated guidelines provide evidence‐based paradigms for the management of locoregionally recurrent rectal cancer (LRRC). This multispecialty committee included gastrointestinal radiation and medical oncology, gastroenterology, radiology, and colorectal surgery.
Eric D. Miller   +18 more
wiley   +1 more source

A dosimetric analysis of a rotating gamma ray system and volumetric modulated arc therapy in retrospective replanning for primary liver cancer

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 6, June 2026.
Abstract Background This study is a retrospective replanning study. For primary liver cancer, radiotherapy is vital for inoperable patients; however, dosimetric data comparing the rotating gamma ray system (RGS) and volumetric modulated arc therapy (VMAT) remains scarce, complicating clinical technique selection. Notably, RGS refers to a body gamma ray
Jiarui Zhang   +8 more
wiley   +1 more source

Cross‐anatomical evaluation of a deep‐learning auto‐contouring system: qualitative, geometric, and dosimetric validation

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 6, June 2026.
Abstract Background Accurate and consistent delineation of target and normal structures is essential for safe and effective radiotherapy. Compared with manual or atlas‐based methods, deep learning‐based auto‐contouring has demonstrated improved efficiency and reduced interobserver variability. However, its performance can vary across anatomical regions
Sara Endo   +4 more
wiley   +1 more source

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

open access: yesAdvanced Functional Materials, Volume 36, Issue 45, 5 June 2026.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez   +8 more
wiley   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu   +9 more
wiley   +1 more source

Bilateral Thalamic Diffuse Midline Glioma, H3K27M‐Altered, in a 3‐Year‐Old Boy

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Diffuse midline glioma, H3 K27‐altered, is an aggressive pediatric brain tumor that can mimic non‐neoplastic conditions when located outside the brainstem. We describe a 3‐year‐old boy who presented with progressive ocular misalignment and left‐sided weakness without systemic symptoms.
Ammir Abuzahra   +7 more
wiley   +1 more source

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