Results 151 to 160 of about 52,263 (284)
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song +15 more
wiley +1 more source
ABSTRACT Introduction 68Ga‐DOTATOC positron emission tomography/computed tomography (PET/CT) targets somatostatin receptors (SSTRs) and is an established molecular imaging modality for neuroendocrine tumors (NETs). Although SSTR expression has been reported in renal cell carcinoma (RCC), its clinical utility remains unclear. Case Presentation A 76‐year‐
Yuta Mine +9 more
wiley +1 more source
Malignant craniopharyngiomas: Institutional experience and literature review
We report the second case of malignant craniopharyngioma with BAP1 and TP53 mutations. A literature review identified 44 cases of malignant craniopharyngiomas with a median overall survival of 6 months. Eighteen (41%) occurred in patients without any history of radiation, suggesting that mechanisms other than radiation have contributed to their ...
Thomas J. Auen +10 more
wiley +1 more source
ABSTRACT Mucous membrane pemphigoid (MMP) following anti‐programmed cell death‐1 (PD‐1) therapy is rare but increasingly reported. Management of high‐ and low‐risk MMP in this setting and the potential oncologic trade‐offs remain poorly defined. We performed a narrative synthesis of all published cases of anti‐PD‐1‐associated MMP, following MEDLINE ...
Serena Dienes +2 more
wiley +1 more source
Abstract This literature‐based systematic review and associated guidelines provide evidence‐based paradigms for the management of locoregionally recurrent rectal cancer (LRRC). This multispecialty committee included gastrointestinal radiation and medical oncology, gastroenterology, radiology, and colorectal surgery.
Eric D. Miller +18 more
wiley +1 more source
Abstract Background This study is a retrospective replanning study. For primary liver cancer, radiotherapy is vital for inoperable patients; however, dosimetric data comparing the rotating gamma ray system (RGS) and volumetric modulated arc therapy (VMAT) remains scarce, complicating clinical technique selection. Notably, RGS refers to a body gamma ray
Jiarui Zhang +8 more
wiley +1 more source
Abstract Background Accurate and consistent delineation of target and normal structures is essential for safe and effective radiotherapy. Compared with manual or atlas‐based methods, deep learning‐based auto‐contouring has demonstrated improved efficiency and reduced interobserver variability. However, its performance can vary across anatomical regions
Sara Endo +4 more
wiley +1 more source
Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez +8 more
wiley +1 more source
Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu +9 more
wiley +1 more source
Bilateral Thalamic Diffuse Midline Glioma, H3K27M‐Altered, in a 3‐Year‐Old Boy
ABSTRACT Diffuse midline glioma, H3 K27‐altered, is an aggressive pediatric brain tumor that can mimic non‐neoplastic conditions when located outside the brainstem. We describe a 3‐year‐old boy who presented with progressive ocular misalignment and left‐sided weakness without systemic symptoms.
Ammir Abuzahra +7 more
wiley +1 more source

