Results 111 to 120 of about 123,216 (307)

I Wanted to Be Able to Stand on My Own Two Feet First—Younger Parents Exiting Homelessness and Care and Their Aspirations

Australian Journal of Social Issues, EarlyView.
ABSTRACT This qualitative study examines the aspirations, motivations and support needs of 15 young parents in South Australia with experiences of out‐of‐home care (OOHC) or homelessness. Most participants aimed to delay parenting to achieve financial stability, education and personal development, but faced unplanned pregnancies due to inadequate ...
Tim Moore, Stewart McDougall
wiley   +1 more source

Assaying Mechanonociceptive Behavior in Drosophila Larvae

Bio-Protocol, 2018
Drosophila melanogaster larvae have been extensively used as a model to study the molecular and cellular basis of nociception. The larval nociceptors, class IV dendritic arborization (C4da) neurons, line the body wall of the animal and respond to various
Nina Hoyer, Meike Petersen, Federico Tenedini, Peter Soba   +3 more
doaj   +1 more source

Behavior Decoding Delineates Seizure Microfeatures and Associated Sudden Death Risks in Mouse Models of Epilepsy

Annals of Neurology, EarlyView.
Objective Behavior and motor manifestations are distinctive yet often overlooked features of epileptic seizures. Seizures can result in transient disruptions in motor control, often organized into specific behavioral sequences that can inform seizure types, onset zones, and outcomes.
Yuyan Shen, Jaden Thomas, Xianhui Chen, Jaden Zelidon, Mariam Najeeb, Abigayle Hahn, Ping Zhang, Aaron Sathyanesan, Bin Gu   +8 more
wiley   +1 more source

Apical-Basal Polarity Signaling Components, Lgl1 and aPKCs, Control Glutamatergic Synapse Number and Function. [PDF]

, 2019
Normal synapse formation is fundamental to brain function. We show here that an apical-basal polarity (A-BP) protein, Lgl1, is present in the postsynaptic density and negatively regulates glutamatergic synapse numbers by antagonizing the atypical protein
Cheng, Hongqiang, Ghosh, Sourav, Hejran, Helen, Klezovitch, Olga, Lee, Su-Yee, Mao, Ye, Mu, Yongxin, Qin, Huaping, Scott, John, Thakar, Sonal, Vasioukhin, Valeri, Yu, Ting, Zou, Yimin   +12 more
core   +1 more source

Human Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in Mice

Annals of Neurology, EarlyView.
Objective Traumatic brain injury (TBI) is an established risk factor for dementia, although the underlying mechanisms remain unclear. Our previous research demonstrated that a single severe TBI in wild‐type (WT) mice induces a prion‐like form of tau (tauTBI) that spreads throughout the brain, leading to memory deficits.
Gloria Vegliante, Francesca Pischiutta, Elena Restelli, Federico Moro, Maria Antonietta Chiaravalloti, Ilaria Raimondi, Ilaria Bertani, Ilaria Lisi, Eliana Sammali, Rosaria Pascente, Serena Scozzari, Laura Pasetto, Carly Douglas, Marco Locatelli, Fabrizio Ortolano, Valentina Bonetto, David J. Loane, Nino Stocchetti, Roberto Chiesa, Elisa R. Zanier   +19 more
wiley   +1 more source

Tourette Syndrome as a Disorder of the Social Decision Making Network

Frontiers in Psychiatry, 2019
Tourette syndrome is a common neurodevelopmental disorder defined by the presence of tics, stereotyped involuntary movements and phonations. Considerable evidence points to developmental abnormalities of the basal ganglia as tic substrates. Basal ganglia
Roger L. Albin, Roger L. Albin, Roger L. Albin, Roger L. Albin   +3 more
doaj   +1 more source

DEVELOPMENT OF COMPLEX, STEREOTYPED BEHAVIOR IN PIGEONS [PDF]

Journal of the Experimental Analysis of Behavior, 1980
A pigeon's peck on one key moved a light down one position in a 5 × 5 matrix of lights, while a peck on another key moved the light across one position. Reinforcement depended upon the occurrence of four pecks on each key (moving the matrix light from the top left to the bottom right), and a fifth peck on either key ended a trial without food.
openaire   +3 more sources

Tau Pathology in Alzheimer's Disease Uniquely Affects Sulcal Depths

Annals of Neurology, EarlyView.
Objective Though it is widely known that tau deposition affects brain structure, the precise localization of these effects is poorly understood, especially in relation to gyral and sulcal anatomy. We investigated whether tau pathology in Alzheimer's disease (AD) preferentially affects sulci, and particularly sulcal depths.
Samira A. Maboudian, Corrina S. Fonseca, Adam C. Martersteck, Yishu Chao, Yuheng Chen, Daniela Ushizima, Duygu Tosun, Lea T. Grinberg, Kevin S. Weiner, William J. Jagust, for the Alzheimer's Disease Neuroimaging Initiative   +10 more
wiley   +1 more source

Dr. Hans Kohn and the political takeover of the Berlin Medical Society by the National Socialist regime in 1933

The Anatomical Record, EarlyView.
Abstract To solidify their power over society, totalitarian regimes will usually eliminate any dissent, any perceived threats early on. These threats include not only political enemies but also educated and independent segments of society, such as professional associations.
Michael Hortsch
wiley   +1 more source

T. rex cognition was T. rex‐like—A critical outlook on diverging views of the neurocognitive evolution in dinosaurs

The Anatomical Record, EarlyView.
Abstract A recent debate has emerged between Caspar et al. (2024) and Herculano‐Houzel (2023) on inferring extinct dinosaur cognition by estimating brain neuron counts. While thought‐provoking, the discussion largely overlooks the function of cognition, as well as partly neglects the difficulties involved in estimating neuron numbers, which according ...
Thomas Rejsenhus Jensen, Ivo Jacobs, Kristina Kverková, Lona Lalić, Alexandra Polonyiová, Patrik Stehlík, Stephan A. Reber, Mathias Osvath   +7 more
wiley   +1 more source