Abstract Objective Appropriate endpoints for daily antiseizure medications may differ from those for intermittent, immediate‐use seizure medications (ISMs). The observed interval between seizure clusters over time (SEIzure interVAL [SEIVAL]) has been proposed as a novel effectiveness endpoint for ISMs.
Wesley T. Kerr +4 more
wiley +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
wiley +1 more source
Evaluating the Efficacy of Repetitive Transcranial Magnetic Stimulation Combined With Auditory Integration Training for Children With Autism Spectrum Disorder: Protocol for a Randomized Sham-Controlled Trial. [PDF]
Hao Q, Wang J, Yang J, Li W, Hu S, Lv Z.
europepmc +1 more source
Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source
Severe Delirium Caused by Short-Term Administration of Compound Paracetamol and Amantadine Hydrochloride Capsules in an Elderly Patient With Extremely Low Body Weight. [PDF]
Dong Y, Wang Y, Qiu Z, Cheng J, Yu Z.
europepmc +1 more source
ABSTRACT Introduction Adolescents with anorexia nervosa (AN) often present cognitive rigidity, impaired decision‐making, and difficulties processing emotions, all of which can impede engagement in treatment. The marked rise in paediatric hospitalisations for AN during the COVID‐19 pandemic highlights the urgent need for brief, targeted interventions in
Dario Marin +4 more
wiley +1 more source
Exploiting large language models for diagnosing autism associated language disorders and identifying distinct features. [PDF]
Hu C +7 more
europepmc +1 more source
Abstract This article explores how Afro‐Brazilian communities in Pernambuco respond to state‐led industrial development through culturally rooted practices of resistance and repair. Drawing on archival and ethnographic research in the coastal municipalities of Cabo de Santo Agostinho and Ipojuca, this study traces the effects of Brazil's large‐scale ...
Shelly Annette Biesel
wiley +1 more source
Progress in exercise interventions for autism spectrum disorder: exploring underlying mechanisms. [PDF]
Wang C, Zhang Y, Zhu J, Lin Z.
europepmc +1 more source
Olfactory mechanisms of stereotyped behavior: on the scent of specialized circuits. [PDF]
Stowers L, Logan DW.
europepmc +1 more source

