ABSTRACT Aim The aim of this Phase I/II open‐label study was to assess the safety and efficacy of NTI164, a novel full‐spectrum medicinal cannabis plant extract 0.08% Δ‐9‐tetrahydrocannabinol (THC), in Rett syndrome (RTT). Methods Eleven female participants (5–16 years) with a pathogenic variant in the MECP2 gene were recruited to this study, receiving
B. A. Keating +7 more
wiley +1 more source
A Multimodal Approach to Treatment and Management of Rumination Syndrome in a California Sea Lion (<i>Zalophus californianus</i>). [PDF]
Ramos AM +8 more
europepmc +1 more source
ABSTRACT Aim This study reviewed the nutritional status, feeding skills, safety, and management of patients with Rett syndrome during childhood and adolescence. Method Retrospective chart review of 103 females with classical Rett syndrome, aged ≤ 18 years, attending a Rett syndrome Multidisciplinary Management clinic in a tertiary hospital from 2000 to
Susan Thompson +3 more
wiley +1 more source
GAMT Deficiency: Clinical Presentation, Treatment, Diagnosis, Animal Models, Preclinical and Clinical Developments. [PDF]
Biagiotti S +9 more
europepmc +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
TOR1AIP2 as a candidate gene for dystonia-hemichorea/hemiballism. [PDF]
Kafantari E +9 more
europepmc +1 more source
Psychogenic polydipsia in dogs – a review of pathogenesis, diagnosis and treatment
Polyuria and polydipsia represent a common clinical presentation in dogs and may result from numerous disorders affecting different body systems. Compulsive water consumption is characteristic of psychogenic polydipsia, a primary polydipsia disorder rooted in neurologic, behavioural or environmental factors.
G. Pavlovsky
wiley +1 more source
Effects of video game-based interventions on executive functions and motor skills in children and adolescents with neurodevelopmental disorders: a systematic review and meta-analysis. [PDF]
Gao M, Ren J, Kaulie A, Wang Q, Gao G.
europepmc +1 more source
The dynamics of cyclic‐periodic phenomena during non‐rapid and rapid eye movement sleep
Summary Sleep is a complex physiological state characterized by distinct stages, each exhibiting unique electroencephalographic patterns and physiological phenomena. Sleep research has unveiled the presence of intricate cyclic‐periodic phenomena during both non‐rapid eye movement and rapid eye movement sleep stages. These phenomena encompass a spectrum
Maria P. Mogavero +5 more
wiley +1 more source
Effects and mechanisms of vitamins A and D on behavior associated with Tourette syndrome in rats. [PDF]
Li LN +8 more
europepmc +1 more source

