Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj +25 more
wiley +1 more source
A Droplet-Based Microfluidic Platform for Rapid Optical Detection of Bacteria: Proof-of-Concept for Radiopharmaceutical Sterility Testing. [PDF]
Colombelli A +7 more
europepmc +1 more source
GmTGA9-GmDYT1 Regulates Anther Wall Development to Affect Male Fertility in Soybean. [PDF]
Wu S +6 more
europepmc +1 more source
Cysteine-rich receptor-like kinase and MADS-box co-regulation of programmed cell death drives apical spikelet degeneration in wheat. [PDF]
Du Q +8 more
europepmc +1 more source
Heat stress impact on rice reproductive processes: challenges and new approaches. [PDF]
Moreira M +5 more
europepmc +1 more source
Positional identification of a candidate gene for MALE STERILITY 2 (MS2) by linkage mapping and transcriptomic data in Cryptomeria japonica D. Don. [PDF]
Ueno S +12 more
europepmc +1 more source
Beyond the Prdm9 model: independent evolution of hybrid male sterility in house mice. [PDF]
Klusáčková P +5 more
europepmc +1 more source
Plant growth-promoting rhizobacteria alleviate drought-stress in upland rice
Costa NB +8 more
europepmc +1 more source
A new estimate of permanent sterility by age: Sterility defined as the inability to conceive
The proportion of couples permanently sterile beyond a certain age is an important component of the reproductive process. Unless medical assistance is used, this age is the upper bound of the fecund period. Most estimates of sterility by age of the woman
Henri Leridon
exaly +2 more sources

