Results 31 to 40 of about 130,729 (314)

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Physical structure changes of solid medium by steam explosion sterilization [PDF]

, 2016
Physical structure changes of solid medium were investigated to reveal effects of steam explosion sterilization on solid-state fermentation (SSF). Results indicated that steam explosion changed the structure of solid medium at both molecular and three ...
Wang, Lan, Chen, Hong-Zhang, Zhao, Zhi-Min   +2 more
core   +1 more source

Construction and validation of a prognostic prediction model for poorly cohesive gastric adenocarcinoma based on inflammatory indices and machine learning

European Journal of Medical Research
Background This study aims to construct a survival prognostic prediction model for poorly cohesive gastric adenocarcinoma patients by combining inflammatory indices and machine learning methods, and to evaluate its clinical application value.
Ying Fu, Xuehui Jin, Yuehua Xu
doaj   +1 more source

Sterilization and disinfection methods for decellularized matrix materials: Review, consideration and proposal

Bioactive Materials, 2021
Sterilization is the process of killing all microorganisms, while disinfection is the process of killing or removing all kinds of pathogenic microorganisms except bacterial spores.
Meihan Tao, Tianrang Ao, Xiaoyan Mao, Xinzhu Yan, Rabia Javed, Weijian Hou, Yang Wang, Cong Sun, Shuang Lin, Tianhao Yu, Qiang Ao, Prof.   +10 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Effect of different sterilization methods on physicochemical and microbiological properties of rice wine

Beni-Suef University Journal of Basic and Applied Sciences, 2018
The present study investigated the effect of three different sterilization methods (high hydrostatic pressure sterilization, ultraviolet sterilization, and ultra-high temperature sterilization) on changes of physicochemical and microbiological properties
Tie-Yan Jin, Kandasamy Saravanakumar, Myeong-Hyeon Wang   +2 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Unlocking the potential of a novel integrated multi-trophic aquaculture (IMTA) approach for producing resilient foods at scale in a post nuclear war world: A perspective exploiting freshwater fish, duckweed and microalgae

Resources, Environment and Sustainability
The global agriculture system governing food security is strongly reliant upon environmental conditions including temperature, precipitation and sunlight, all of which could be significantly disrupted by a catastrophe such as a nuclear war.
Neil J. Rowan, Marcel A.K. Jansen, Peter Klimek   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

405 nm violet-blue light inactivates hepatitis C cell culture virus (HCVcc) in ex vivo human platelet concentrates and plasma

Scientific Reports
Added safety measures coupled with the development and use of pathogen reduction technologies (PRT) significantly reduces the risk of transfusion-transmitted infections (TTIs) from blood products.
Joseph W. Jackson, Pravin R. Kaldhone, Caitlin Stewart, John Anderson, Scott MacGregor, Michelle Maclean, Marian Major, Chintamani D. Atreya   +7 more
doaj   +1 more source