Results 261 to 270 of about 404,363 (354)

S2k-Guideline Non-hormonal Contraception, Part 2: Intrauterine Devices and Sterilization: Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015 - 095, January 2024).

open access: yesGeburtshilfe Frauenheilkd
Böttcher B   +30 more
europepmc   +1 more source

Impact of Mutational Status on Intracellular Effects of Cell‐Permeable CaaX Peptides in Pancreatic Cancer Cells

open access: yesChemBioChem, EarlyView.
This work deals with intracellular effects of cell‐permeable CaaX‐peptides, designed to influence prenylated proteins like KRas. The results show that after CaaX‐1 treatment, not only KRas expression and signaling are specifically altered in mutated pancreatic cancer cells, but also plasma membrane localization of KRas is affected.
Merlin Klußmann   +2 more
wiley   +1 more source

Scrambled RGD Hexameric Peptide Hydrogel Supports Efficient Self‐Assembly and Cell Activity

open access: yesChemistry – A European Journal, EarlyView.
Self‐assembled peptide hydrogels that incorporate bioactive motifs such as the integrin‐binding epitope Arginine‐Glycine‐Aspartic acid (RGD), are known for supporting cell growth. Surprisingly, scrambling the peptide cell‐adhesion motif RGD to RDG in an Fmoc‐hexapeptide peptide gelator (Fmoc‐GFFRGD) results in superior properties in terms of minimum ...
Karrar Al Taief   +4 more
wiley   +1 more source

Removal of benzotriazoles from domestic wastewater using Pleurotus ostreatus fungal pellets

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Removal of benzotriazoles from domestic wastewater using a fungal pellet reactor with Pleurotus ostreatus. The system effectively removed CBTR (70%), while BTR (19%), 5‐TTR (17%), and OH‐BTH (16%) showed moderate removal. Abstract Benzotriazoles are a group of persistent and mobile substances commonly found in aquatic environments due to inefficient ...
Evrydiki Markoulatou   +3 more
wiley   +1 more source

Multiscale hamstring muscle adaptations following 9 weeks of eccentric training. [PDF]

open access: yesJ Sport Health Sci
Andrews MH   +7 more
europepmc   +1 more source

Actin Isovariant ACT2‐Mediated Cellular Auxin Homeostasis Regulates Lateral Root Organogenesis in Arabidopsis thaliana

open access: yesCytoskeleton, EarlyView.
ABSTRACT Lateral root (LR) organogenesis is regulated by cellular flux of auxin within pericycle cells, which depends on the membrane distribution and polar localization of auxin carrier proteins. The correct distribution of auxin carrier proteins relies on the intracellular trafficking of these proteins aided by filamentous actin as a track.
Aya Hanzawa   +2 more
wiley   +1 more source

New Pyridobenothiazolone Derivatives Display Nanomolar Pan‐Serotype Anti‐Dengue Virus Activity

open access: yesChemMedChem, EarlyView.
A ligand‐based strategy is employed, starting from hit compound 2, to develop the C‐2 modified pyridobenzothiazolone 19 as a pan‐serotype nanomolar DENV‐1‐4 inhibitor. Investigations of the mechanism reveal the peculiar ability to abolish the infectivity of virions in a second infection.
Tommaso Felicetti   +13 more
wiley   +1 more source

Grape Stalks Valorization towards Circular Economy: A Cascade Biorefinery Strategy

open access: yesChemSusChem, EarlyView.
A cascade protocol for grape stalks valorization has been proposed, characterized by a multidisciplinary strategy using unconventional techniques and subcritical water as a green solvent, where physical/chemical treatments synergistically interact with biological treatments to obtain added value products from all the biomass components.
Carlotta Valle   +11 more
wiley   +1 more source

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