Results 201 to 210 of about 4,335 (247)

Population Pharmacokinetic and Exposure‐Response Analysis of the Cognitive Effects of TAK‐071 in Participants With Parkinson Disease and Cognitive Impairment

Clinical Pharmacology in Drug Development, EarlyView.
Abstract TAK‐071 is a novel muscarinic M1 positive allosteric modulator under investigation for the treatment of cognitive impairment and falls associated with Parkinson disease (PD). This study evaluated population pharmacokinetics of TAK‐071 following single (1‐160 mg) and multiple (3‐15 mg once daily) oral‐dose TAK‐071 in 112 healthy participants ...
Hongxia Jia, Axel Facius, Rachel Jennings, Yaming Hang, Jaya Padmanabhan, Niraj M. Shanbhag, Brian T. Harel, Arthur Simen, Wei Yin   +8 more
wiley   +1 more source

Diclofenac Detection via Inner‐Filter Effect Using Pyridine‐Modified Triphenylene

ChemPlusChem, EarlyView.
The synthesis of hexa‐pyridine triphenylene derivatives via Suzuki‐coupling reaction and their application toward the sensing of diclofenac have been studied for the first time. The 3PY and 4PY are selective for diclofenac over the other commonly prescribed pharmaceuticals and hormones tested. Triphenylene derivatives 3PY (2,3,6,7,10,11‐hexa(pyridine‐3‐
Navdeep Kajal, Amar Raj, Rajendhraprasad Tatikonda, Jan Lundell, Matti Haukka   +4 more
wiley   +1 more source

The Type of Follicle‐Stimulating Hormone Medication Given for In Vitro Fertilization Impacts Oocyte Retrieval: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Understanding the variability in ovarian response following administration of follicle‐stimulating hormone medications in women undergoing in vitro fertilization may help inform prescribing decisions. A systematic review was conducted to compare the number of retrieved oocytes and fertility outcomes following the administration of different follicle ...
Toni J.F. Michael, Ranita Kirubakaran, Tanay Parab, Rui Wang, Mark Grosser, Beverley J. Vollenhoven, Vinayak Smith, Sophie L. Stocker, on behalf of the LIFE Consortium, Beverley Vollenhoven, Franca Agresta, Mian Bi, Emanuel Birru, David Coman, Nicholas Devereaux, David Gardner, Mark Grosser, Grant Hatamosa, Fabrizzio Horta, Hua Lin, David Listijono, Gavin Sacks, Vinayak Smith, Kate Stern, Sophie Stocker, Steven Tipper, Deon Venter, Rui Wang   +27 more
wiley   +1 more source

Fluorescence Lifetime Based Probes for Water Mediated Proton Transfer and Weak Bases

ChemPhotoChem, EarlyView.
Two hydroxybenzoic acid substituted diazaoxatriangulenium (DAOTA+) fluorescence lifetime probes, is synthesized and which is capable of reporting on intra‐ and intermolecular proton transfer (PT)rates in water. Intramolecular PT in these probes only can happen via Grotthuss‐like water bridging between the carboxylate proton acceptor and the phenol ...
Marko H. Nowack, Bo W. Laursen
wiley   +1 more source

The Public Sphere as a Meaningful Arena for Volunteering Dynamics: The Case of a Rural Space in Northern Israel

Conflict Resolution Quarterly, EarlyView.
ABSTRACT This article examines the context of the rural public sphere as reflected in residents' consciousness of their volunteering potential. To this end, a qualitative study was conducted in two rural settlements belonging to the same regional municipality in northern Israel: one Jewish and the other Arab. The 32 interviewees who participated in the
Yasmin Aboud‐Halabi, Galit Yanay‐Ventura   +1 more
wiley   +1 more source

The Enigma of Intra‐Team Collaboration in the Digital Era: The Contribution of Conflict Management and Leadership Patterns, Choice of Communication Mode, and Work Engagement

Conflict Resolution Quarterly, EarlyView.
ABSTRACT This study sought to expand knowledge about the contribution of team processes—conflict management patterns and leadership patterns, the choice of communication mode to deal with various conflicts, and team members' individual and collective work engagement to intra‐team collaboration in teams working in a hybrid format.
Shirly Rozen, Helena Desivilya Syna, Maayan Katzir   +2 more
wiley   +1 more source

Socialization of Prospective Practitioners Towards Pro‐Sustainability Business Attitudes: The Business Curriculum and Social Referents

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Transforming current business practices is key to addressing urgent sustainability grand challenges. To achieve such transformation, we first must foster the internalization of pro‐sustainability business attitudes among prospective business practitioners.
Justo Alberto Ramírez‐Franco, Raquel Antolín‐López, Iván Montiel   +2 more
wiley   +1 more source

Schwannoma of the Sternum [PDF]

The Annals of Thoracic Surgery, 2010
A primary sternal tumor is rare, and it is difficult to make an accurate diagnosis. We herein report a case of intraosseous schwannoma of the sternum, which was associated with various difficulties in regard to making an accurate preoperative diagnosis. A 38-year-old woman underwent a surgical resection for a sternal tumor.
Kohei Yokoi, Tetsuo Taniguchi, Tetsuya Mizuno, Takehiko Okagawa, Koji Kawaguchi, Noriyasu Usami   +5 more
openaire   +2 more sources

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Sternum

2023
Sternum fractures in children are very rare (0.004-0.07% of all paediatric fractures) with an increasing incidence with age. Sternum fractures may result from a direct or an indirect trauma. Most cases are the result of falls or high velocity trauma mechanisms.
Bilo, Rob A.C., Robben, Simon G.F., Van Rijn, Rick R.   +2 more
openaire   +2 more sources

Osteoblastoma of the sternum [PDF]

Archives of Orthopaedic and Traumatic Surgery, 1987
Osteoblastoma has become a well defined bone tumor since its first description by Jaffe and Mayer in 1932. This tumor was considered to occur in almost any bone of the skeleton. Only one previous case of sternal osteoblastoma was described in the literature.
Lin E, S. Oliver, Nerubay J, Alexander Blankstein, Y. Lieberman, J. J. Bubis   +5 more
openaire   +2 more sources