Results 101 to 110 of about 482,487 (316)
Recurrent cranio-oculo-facial diabetic complication
Diabetic cranial neuropathy is one of the important complications of diabetes with up to 10-fold increase in incidence. It usually affects 3rd, 4th, and 6th cranial nerves.
Anupam Dey
doaj +1 more source
Novel Nongenomic Signaling by Glucocorticoid May Involve Changes to Liver Membrane Order in Rainbow Trout [PDF]
Stress-induced glucocorticoid elevation is a highly conserved response among vertebrates. This facilitates stress adaptation and the mode of action involves activation of the intracellular glucocorticoid receptor leading to the modulation of target gene expression. However, this genomic effect is slow acting and, therefore, a role for glucocorticoid in
arxiv
Machine Learning‐Enabled Drug‐Induced Toxicity Prediction
Unexpected toxicity accounts for 30% of drug development failures. This review highlights ML innovations in predicting drug‐induced toxicity, emphasizing comparative analyses, interpretable algorithms, and multi‐source data integration. It categorizes toxicity types, summarizes ML models, and organizes key databases, offering strategies to address ...
Changsen Bai+5 more
wiley +1 more source
Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang+18 more
wiley +1 more source
Steroids are primarily present in human fluids in their sulfated forms. Profiling of these compounds is important from both diagnostic and physiological points of view.
Alberto Sánchez-Guijo+4 more
doaj
Inadvertent steroid injection into the crystalline lens
Intravitreal triamcinolone is administered for a wide number of vitreoretinal conditions. Several complications including cataract formation, raised intraocular pressure, and endophthalmitis have been reported following intravitreal injections. We report
Alam, Md. Shahid, Khetan, Vikas
doaj +1 more source
BERTQA -- Attention on Steroids [PDF]
In this work, we extend the Bidirectional Encoder Representations from Transformers (BERT) with an emphasis on directed coattention to obtain an improved F1 performance on the SQUAD2.0 dataset. The Transformer architecture on which BERT is based places hierarchical global attention on the concatenation of the context and query.
arxiv
In this study, a comprehensive single‐cell transcriptome atlas of the Dezhou donkey, encompassing 20 tissues and 275 050 cells, is constructed. Through cross‐species and cross‐tissue analyses, distinct transcriptional patterns in donkey sebocytes are identified.
Yu Tian+11 more
wiley +1 more source
Regulatory effect of gut microbes on blood pressure
The interaction between gut microbiota and hypertension, the genera which affect the blood pressure in taxonomic level, and the commonly used treatments to hypertension based on the gut microbes were summarized in this review. The increases of Lactobacillus, etc.
Dong Yan+6 more
wiley +1 more source
Due to the delicious taste and remarkable bioactivities of Meretrix meretrix L., they have garnered attention in food field. However, the challenge arises when attempting to separate proteins from crude polysaccharides with similar polarity and ...
Yong Zhu+7 more
doaj +1 more source