Results 121 to 130 of about 890,702 (316)

Psychological traits associated with anabolic androgenic steroid use and dependence: an exploratory cross-sectional study among female athletes

open access: yesBMC Women's Health
Background Anabolic–androgenic steroids (AAS) are commonly taken to increase muscle size and enhance performance. However, AAS can lead to many adverse effects, including challenges with mental health and behavior.
Morgan Scarth   +3 more
doaj   +1 more source

The effect of ethanol on cortisol metabolism in man : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University. [PDF]

open access: yes, 1979
Methods were developed for the estimation of human plasma cortisol by radioimmunoassay and urinary 6β-hydroxycortisol (6βOHF) by colorimetry after separation by thin layer chromatography (TLC).
Evans, Pandora Carlyon
core  

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

open access: yesAdvanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad   +2 more
wiley   +1 more source

Molecular Mechanism for the Selective Presentation of Antigenic Peptides by Major Histocompatibility Complex Class I and Class II Molecules: A Hypothesis

open access: yesCurrent Issues in Molecular Biology
The major histocompatibility complex (MHC) class I and class II molecules (abbreviated as MHC-I and MHC-II, respectively) are specialized in antigen presentation.
Bao Ting Zhu
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Study of a Novel Bi‐Layered Thermoplastic Polyurethane Patch for Congenital Diaphragmatic Hernia

open access: yesAdvanced Materials Interfaces, EarlyView.
Large congenital diaphragmatic hernia remains a challenge due to the poor compatibility of current prostheses. To tackle this problem, a bilayer thermoplastic polyurethane patch with tunable mechanical properties is engineered, whose fibrous side supports rapid fibroblast and myoblast colonization, while the smooth film limits adhesions.
Guillaume Leks   +14 more
wiley   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

open access: yesAdvanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun   +7 more
wiley   +1 more source

A novel deproteinization method from crude polysaccharides of Meretrix meretrix Linnaeus based on palygorskite‐chitosan composite aerogel sieving effect

open access: yeseFood
Due to the delicious taste and remarkable bioactivities of Meretrix meretrix L., they have garnered attention in food field. However, the challenge arises when attempting to separate proteins from crude polysaccharides with similar polarity and ...
Yong Zhu   +7 more
doaj   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

open access: yesAdvanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo   +15 more
wiley   +1 more source

Orbital pseudotumour masquerading as Wegener’s granulomatosis [PDF]

open access: yes, 2015
A twenty-two year old female patient presented with new onset bilateral hard orbital masses and progressively worse tear lake problems. Computed tomography of the orbits revealed poorly differentiated bilateral orbital masses.
Fenech, Matthew, Fenech, Thomas
core  

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