Results 131 to 140 of about 1,020,715 (314)

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

The chemicalome profiling of Zishen Yuzhen Pill in vivo and its promoting effect on osteogenic differentiation of MC3T3-E1 cells

Frontiers in Analytical Science
Zishen Yuzhen Pill (ZYP) is a Chinese herbal product developed by Shenzhen TCM Hospital, which have been frequently used to treat osteoporosis (OP).
Juanjuan Cheng, Xinyue Meng, Daozheng Fang, Yong Zhu, Zhihao Liu, Xinyue Li, Ke Jie, Ke Jie, Ke Jie, Shiying Huang, Huilin Li, Shangbin Zhang, Jihang Chen, Jianping Chen   +13 more
doaj   +1 more source

Vasopressin, steroids and epinephrine and neurologically favourable survival after in-hospital cardiac arrest [PDF]

, 2014

openalex   +1 more source

SAFETY AND EFFICACY OF A LOW DOSE CORTICOSTEROID REGIMEN FOR THE INDUCTION TREATMENT OF LUPUS NEPHRITIS - CYCLONES TRIAL: CYCLOPHOSPHAMIDE LOW DOSE AND NO EXTRA STEROID

, 2021
Michelle Lopes, Sandra Gofinet Pasoto, Emily Figueiredo Neves Yuki, Lorena Elizabeth Betancourt Villamarín, Francisco Fellipe Claudino Formiga, Débora Cordeiro do Rosário, L.M.K.R. Brandão, Carolina Torres Ribeiro, Tatiana do Nascimento Pedrosa, Alex Cardoso Lopes, Eduardo Ferreira Borba, Luciana Parente Costa Seguro, Nádia Emi Aikawa, Eloísa Bonfá   +13 more
openalex   +1 more source

Advances in Conductive Nanomaterials for Cardiac Arrhythmia and Future Directions in Bioevaluation Strategies

Advanced Healthcare Materials, EarlyView.
Conductive nanomaterials (CNMs) show promising potential in cardiac tissue regeneration and restoring cardiac rhythm as reported in several in vitro studies. This review article elaborates on the applications of CNMs in the treatment of myocardial infarction (MI) and MI‐induced cardiac arrhythmias, and it sheds light on the innovative approach of ...
Sumithra Y. Srinivasan, Anna Laromaine
wiley   +1 more source

Disappearance of Glomerular IgA Deposits in Steroid-Responsive Nephrotic Syndrome [PDF]

, 1989
K. Fukushi, Hideaki Yamabe, Kazuhiro Ozawa, Hiroshi Ohsawa, Noriyuki Chiba, Hiroshi Inuma, Satoshi Seino, Mariko Miyata, Kogo Onodera   +8 more
openalex   +1 more source

Data from Steroid Hormone Receptor and Infiltrating Immune Cell Status Reveals Therapeutic Vulnerabilities of <i>ESR1</i>-Mutant Breast Cancer

, 2023
Michelle M. Williams, Nicole S. Spoelstra, Spencer Arnesen, Kathleen O’Neill, Jessica L. Christenson, Jordan Reese, Kathleen C. Torkko, Andrew Goodspeed, Emmanuel Rosas, Toru Hanamura, Sharon B. Sams, Zheqi Li, Steffi Oesterreich, Rebecca B. Riggins, Britta M. Jacobsen, Anthony Elias, Jason Gertz, Jennifer K. Richer   +17 more
openalex   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

A Novel First-Line Treatment Alternative for Noncomplicated Idiopathic Granulomatous Mastitis: Combined İntralesional Steroid İnjection with Topical Steroid Administration [PDF]

, 2020
Osman Toktaş, Can Konca, Didem Can Trabulus, Aykut Soyder, Hande Köksal, Hasan Karanlık, Ayfer Kamalı Polat, Serdar Özbaş, Serdar Yormaz, Arda Işık, Efe Sezgın, Atilla Soran   +11 more
openalex   +1 more source