Results 181 to 190 of about 1,100,762 (364)

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Tubercular Optochiasmatic Arachnoiditis: A Case Report with Current Therapeutics and Management

Libyan International Medical University Journal, 2023
Satish Swain, Akansha Didwania, Abhishek Anand, Upendra Baitha   +3 more
doaj   +1 more source

Patterns of steroid use in patients with established rheumatoid arthritis commencing treatment with biologic or targeted synthetic DMARDs. [PDF]

Rheumatol Adv Pract
Stadler M, Bindra S, Cheung A, Yap CF, Bluett J, Plant D, Nair N, Hyrich K, Morgan A, Wilson AG, Isaacs JD, Barton A.   +11 more
europepmc   +1 more source

Sex Hormone-Binding Globulin in Fish Gills Is a Portal for Sex Steroids Breached by Xenobiotics [PDF]

, 2008
Solange Miguel-Queralt, Geoffrey L. Hammond   +1 more
openalex   +1 more source

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

Advanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi, Song Wang, Yuqing Yan, Wei Chen, Yingying Cao, Dafan Chen, Wei Chen, Caiyun Ma, Xinjian Wan   +8 more
wiley   +1 more source

Steroidal Compounds at the Crossroads of Inflammation and Cancer: Implications for Drug Discovery and Therapy. [PDF]

Biomedicines
Dembitsky VM, Terent'ev AO.
europepmc   +1 more source

Diagnostic Study of a Synthetic Human Corticotropin-Releasing Hormone (hCRH) in Healthy Adult Males: Its Plasma Pharmacokinetics and the Effects on the Urinary Excretion of Steroid Hormones.

, 1993
KOSHI TANAKA, MECUMI NAGATA, Sachiko Itoh, Munehito Kumagae, N Shimizu   +4 more
openalex   +2 more sources

Notch2 Directs aTreg Cell Fate toward Immunoregulation or Inflammatory Pyroptosis

Advanced Science, EarlyView.
Schematic illustration showing that the Notch2 intracellular domain (NICD2) facilitates pyroptosis resistance in activated Tregs through the RREB1/Foxo1 signaling pathway. In addition, Notch2‐mediated pyroptosis resistance in activated Tregs promotes immunoregulatory capacity, thereby attenuating Th2‐driven inflammatory responses in allergic rhinitis ...
Yue‐Long Qiao, Shan Xu, You Zou, Rui Yang, Han Zheng, Jia‐Yu Liu, Hui‐Ming Fan, Yuan‐Yuan Zhang, Yong‐Gang Kong, Wo‐Er Jiao, Shi‐Ming Chen   +10 more
wiley   +1 more source

Radiofrequency ablation for giant congenital lung malformations complicated by fetal hydrops: a retrospective case series. [PDF]

Arch Gynecol Obstet
Qin F, Huang T, Luo X, Luo W, Xu X, Yang Y, Chen X, Tian X, Kang D, Liu Y, Chen G.   +10 more
europepmc   +1 more source

Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research

Journal of neuroendocrinology, 2016
Patrizia Porcu, Anna M. Barron, Cheryl A. Frye, Cheryl A. Frye, A. Walf, A. Walf, A. Walf, S. Yang, X. He, A. Morrow, Giancarlo Panzica, R. Melcangi   +11 more
semanticscholar   +1 more source