Results 211 to 220 of about 1,100,762 (364)

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun, Jie Liu, E Xiang, Xia Li, Xuerong Yan, Yuxi Wang, Feng Li, Hao Kou, Hui Wang, Yu Guo   +9 more
wiley   +1 more source

IL6 blockade: an effective approach in steroid-refractory immune checkpoint inhibitor-related neuropathies requiring ICI rechallenge-case report. [PDF]

ESMO Open
Baek C, Kramkimel N, Mélé N, Lenglet T, Psimaras D, Birzu C.   +5 more
europepmc   +1 more source

In vitro effects of steroids on catecholamine responses of the isolated rabbit uterus

, 1975
Taiichi Saito, Hiroshi Yoshida, H Kawaguchi, Yoshikatsu Nakamoto   +3 more
openalex   +1 more source

Mass spectrometry and immunoassay: how to measure steroid hormones today and tomorrow.

European Journal of Endocrinology, 2015
A. Taylor, B. Keevil, I. Huhtaniemi
semanticscholar   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

Continuing anticoagulant and antiplatelet drugs in patients undergoing cervical transforaminal epidural steroid infiltraties: Is the benefit worth the risk? [PDF]

Interv Pain Med
Peene L.
europepmc   +1 more source

Delayed Pneumocephalus Following Fluoroscopy Guided Cervical Interlaminar Epidural Steroid Injection: A Rare Complication and Anatomical Considerations [PDF]

, 2015
Yeon-Dong Kim, Hyang-Do Ham, Hyun-Seog Moon, Soo-Han Kim   +3 more
openalex   +1 more source

Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury

Advanced Science, EarlyView.
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng, Zhaowei Zhang, Zezhou Fu, Qingqing Wang, Siwen Zhang, Tingyu Zhang, Meifei Zhu, Shunwu Fan, Youqing Shen, Jiajia Xiang, Xin Liu   +10 more
wiley   +1 more source

Clinicopathological features of steroid-refractory immune-mediated hepatotoxicity induced by immune checkpoint inhibitors. [PDF]

BMC Gastroenterol
Hioki T, Imoto K, Goya T, Azuma Y, Horiuchi A, Aoyagi T, Takahashi M, Oda Y, Kato M, Kohjima M, Tanaka M, Ogawa Y.   +11 more
europepmc   +1 more source

Nanozyme‐Integrated Hydrogel Targeting AGEs for Diabetic Osteoarthritis Therapy

Advanced Science, EarlyView.
A nanozyme–integrated hydrogel (PTC‐MP) exhibiting with mild photothermal effects is constructed, and a “3R” (restrain‐restore‐reinforce) strategy is proposed for diabetic osteoarthritis (DOA) treatment based on advanced glycation end products (AGEs) targeting.
Rui Chen, Yanguo Su, Guiyuan Zhao, Jiaojiao Tao, Qijie Diao, Guangli Xiang, Tianze Jiang, Lu Han, Xia Zhao   +8 more
wiley   +1 more source