Results 231 to 240 of about 1,100,762 (364)

Letter to editor: Intradiscal steroid injection for lumbar canal stenosis: novel but not yet ready for clinical adoption. [PDF]

Asian Spine J
Khurana G, Singla V, Ghai B.
europepmc   +1 more source

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

Advanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye, Jianfeng Xiang, Siqi Zhou, Qintao Ge, Aihetaimujiang Anwaier, Kun Chang, Gang Wei, Jiahe Lu, Xi Tian, Shuxuan Zhu, Yuchen Jiang, Wei Zhang, Tingting Cai, Moran Xu, Dingwei Ye, Danfeng Xu, Tao Wang, Hailiang Zhang, Wenhao Xu   +18 more
wiley   +1 more source

Cholesterol and steroid synthesis pathways may be involved in the inhibition of osteosarcoma cell viability by calcium-sensing receptor antagonism. [PDF]

PeerJ
Wang L, Wang J, Chu X, Liu Y, Fan Y, Qi X, Guo J, Wang S.   +7 more
europepmc   +1 more source

A Supramolecular Nanoscavengers: Based “Cargo‐Exchange” Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy

Advanced Science, EarlyView.
Dysregulated cholesterol metabolism, driven by a complex array of mechanisms, is a defining characteristic of glioblastoma (GBM). In this study, supramolecular nanoscavengers are engineered by harnessing the intrinsic binding affinity between endogenous small‐molecule cholesterol and β‐cyclodextrin (β‐CD).
Zonghua Tian, Yun Chen, Jingyi Zhou, Shilin Zhang, Hongrui Fan, Xuwen Li, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source

Adrenal Crisis Masquerading as Sepsis in a Patient With Autoimmune Multimorbidity: A Diagnostic Challenge on the Acute Medical Ward. [PDF]

Cureus
Reyad B, Aldawoody H.
europepmc   +1 more source

Human endometrium transplanted into nude mice. Histologic effects of various steroid hormones.

, 1985
Agneta Bergqvist, Sten Jeppsson, Stig Kullander, Otto Ljungberg   +3 more
openalex   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

A rare case report of iatrogenic Cushing syndrome with multisystem involvement due to prolonged steroid injections: a diagnostic challenge. [PDF]

Ann Med Surg (Lond)
Ali T, Javaid MH, Khalid M, Javed M, Zeb M, Afridi S, Bangash K.   +6 more
europepmc   +1 more source

Steroid Receptor Coactivator 2 Is Critical for Progesterone-Dependent Uterine Function and Mammary Morphogenesis in the Mouse

, 2006
Atish Mukherjee, Selma M. Soyal, Rodrigo Fernandez‐Valdivia, Martine Géhin, Pierre Chambon, Francesco J. DeMayo, John P. Lydon, Bert W. O’Malley   +7 more
openalex   +1 more source

Stereoselective Ferrier‐Type O‐Glycosylation Enabled by Difluoromethylated Glycal Donors

Advanced Science, EarlyView.
A fluorine‐mediated stereoselective Ferrier‐type glycosylation is reported. Glycals are pre‐decorated with photo‐2‐difluoroalkylation and reacted with diverse acceptors to obtain exclusively α‐selective Ferrier rearrangement products. Abstract The effective construction of structurally homogeneous glycosides is requisite in oligosaccharide assembly and
You Zou, Hengfu Xu, Cang‐Xin Zheng, Weiwei Zhang, Xin‐Shan Ye, De‐Cai Xiong   +5 more
wiley   +1 more source