Results 21 to 30 of about 181,670 (303)
Behavioral and Brain Functions, 2019 Background Age-dependent alterations of hormonal states have been considered to be involved in age related decline of cognitive abilities. Most of the studies in animal models are based on hormonal substitution in adrenal- and/or gonadectomized rodents ...
Jovana Maliković +10 more
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Steroid Hormones: Membrane transporters of steroid hormones [PDF]
Current Biology, 1995 The discovery of a plasma membrane ABC protein that exports steroids in yeast highlights the possibility that similar membrane sorting systems in mammalian cells may modulate the access of steroids to their receptors.
openaire +2 more sources
Disruption of histone modification and CARM1 recruitment by arsenic represses transcription at glucocorticoid receptor-regulated promoters. [PDF]
PLoS ONE, 2009 Chronic exposure to inorganic arsenic (iAs) found in the environment is one of the most significant and widespread environmental health risks in the U.S. and throughout the world.
Fiona D Barr +3 more
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Frontiers in Oncology, 2022 Steroid hormones govern the complex, cyclic changes of the endometrium, predominantly through their receptors. An interplay between steroid hormones and epigenetic mechanisms controls the dynamic endometrial gene regulation.
Vishakha Mahajan +7 more
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Scientific Reports, 2023 The content of androgen from adrenal is elevated under castration, and the mechanisms of compensatory secretion of adrenal androgen remain unknown.
Haijing Jing +4 more
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Role of glucocorticoid metabolism in childhood obesity-associated hypertension
Endocrine Connections, 2022 Objective: Childhood obesity is associated with alterations in hypothalamus–pituitary– adrenal axis activity. We tested the hypothesis that multiple alterations in the metabolism of glucocorticoids are required for the development of hypertension in ...
Martijn J J Finken +8 more
doaj +1 more source
Regulation of ecdysone production in Drosophila by neuropeptides and peptide hormones [PDF]
Open Biology, 2021 In both mammals and insects, steroid hormones play a major role in directing the animal's progression through developmental stages. To maximize fitness outcomes, steroid hormone production is regulated by the environmental conditions experienced by the ...
Jade R. Kannangara +2 more
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Frontiers in Genetics, 2022 Background: The etiology of preeclampsia (PE) remains unclear. With the utilization of metabolomics, dysregulated production of several metabolic components in human plasma, such as lipids, amino acids, androgens and estrogens, was found to be important ...
Yan Feng +4 more
doaj +1 more source
Frontiers in Physiology, 2021 Sex differences in cerebrovascular disease rates indicate a possible role for ovarian sex steroid hormones in cerebrovascular function. To synthesise and identify knowledge gaps, a systematic review and meta-analysis was conducted to assess how ovarian ...
Bethany D. Skinner +8 more
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Molecular Autism, 2023 Background Prenatal exposure to maternal metabolic conditions associated with inflammation and steroid dysregulation has previously been linked to increased autism risk.
Deborah A. Bilder +6 more
doaj +1 more source