Results 41 to 50 of about 181,670 (303)

The reciprocal regulation of stress hormones and GABAA receptors

Frontiers in Cellular Neuroscience, 2012
Stress-derived steroid hormones regulate the expression and function of GABAA receptors (GABAARs). Changes in GABAAR subunit expression have been demonstrated under conditions of altered steroid hormone levels, such as stress, as well as following ...
Istvan eMody, Jamie eMaguire
doaj   +1 more source

Steroid hormone signaling during development has a latent effect on adult male sexual behavior in the butterfly Bicyclus anynana. [PDF]

PLoS ONE, 2017
It is well established that steroid hormones regulate sexual behavior in vertebrates via organizational and activational effects. However, whether the organizational/activational paradigm applies more broadly to the sexual behavior of other animals such ...
Ashley Bear, Kathleen L Prudic, Antónia Monteiro   +2 more
doaj   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Prostate cancer and therapeutic challenges

Journal of Biological Research - Thessaloniki, 2020
Prostate cancer (PC) is the most prevalent type of cancer in men worldwide. In Saudi Arabia, the rate of PC is increasing annually. The sex steroid hormones androgens and their receptors have critical roles in PC development and progression. Additionally,
Yousef MohammedRabaa Hawsawi, Samar Abdullah Zailaie, Atif Abdulwahab A. Oyouni, Othman Rashed Alzahrani, Osama Mohamed Alamer, Saad Ali S. Aljohani   +5 more
doaj   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Histopathological analysis potential for unveiling hormone signaling in endocrine-related tumors

Endocrine Oncology
Elucidating the mechanisms of action of steroid hormones will contribute to the development of therapeutic strategies for hormone-dependent tumors. Recent advances in genetic engineering have revealed the complex and diverse mechanisms of steroid hormone
Yasuhiro Miki, Erina Iwabuchi, Chihiro Inoue, Yuto Yamazaki, Takashi Suzuki   +4 more
doaj   +1 more source

The Insect Prothoracic Gland as a Model for Steroid Hormone Biosynthesis and Regulation

Cell Reports, 2016
Steroid hormones are ancient signaling molecules found in vertebrates and insects alike. Both taxa show intriguing parallels with respect to how steroids function and how their synthesis is regulated.
Qiuxiang Ou, Jie Zeng, Naoki Yamanaka, Christina Brakken-Thal, Michael B. O’Connor, Kirst King-Jones   +5 more
doaj   +1 more source

Persistent organochlorine pollutants with endocrine activity and blood steroid hormone levels in middle-aged men. [PDF]

PLoS ONE, 2013
BACKGROUND: Studies relating long-term exposure to persistent organochlorine pollutants (POPs) with endocrine activities (endocrine disrupting chemicals) on circulating levels of steroid hormones have been limited to a small number of hormones and ...
Elise Emeville, Frank Giton, Arnaud Giusti, Alejandro Oliva, Jean Fiet, Jean-Pierre Thomé, Pascal Blanchet, Luc Multigner   +7 more
doaj   +1 more source

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman, David G. Stouffer, Dae‐Gyu Jang, Jihyun Park, Benjamin J. Murdock, Richard J. Auchus   +5 more
wiley   +1 more source

Rapid Assessment of Insect Steroid Hormone Entry Into Cultured Cells

Frontiers in Physiology, 2022
Steroid hormones control development and homeostasis in a wide variety of animals by interacting with intracellular nuclear receptors. Recent discoveries in the fruit fly Drosophila melanogaster revealed that insect steroid hormones or ecdysteroids are ...
Mitchell Masterson, Riyan Bittar, Riyan Bittar, Hannah Chu, Naoki Yamanaka, Sachiko Haga-Yamanaka   +5 more
doaj   +1 more source