Results 51 to 60 of about 509,885 (240)

Corticosteroid Activation of Atlantic Sea Lamprey Corticoid Receptor: Allosteric Regulation by the N-terminal Domain [PDF]

open access: yesarXiv, 2022
Lampreys are jawless fish that evolved about 550 million years ago at the base of the vertebrate line. Modern lampreys contain a corticoid receptor (CR), the common ancestor of the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), which first appear in cartilaginous fish, such as sharks.
arxiv  

Neurogenomic landscape associated with status‐dependent cooperative behaviour

open access: yesMolecular Ecology, EarlyView.
Abstract The neurogenomic mechanisms mediating male–male reproductive cooperative behaviours remain unknown. We leveraged extensive transcriptomic and behavioural data on a neotropical bird species (Pipra filicauda) that performs cooperative courtship displays to understand these mechanisms.
Peri E. Bolton   +6 more
wiley   +1 more source

Multi‐omics analysis of the regulatory network in winter buds of ‘Cabernet Sauvignon’ grapevine from dormancy to bud break

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Winter dormancy and bud break are crucial to the viability, adaptability and yield of fruit trees, but not all metabolic activities or regulatory factors involved in maintaining and breaking dormancy are known. Here, winter buds, spanning from natural dormancy to bud break, were collected from ‘Cabernet Sauvignon’ grapevines maintained outdoors
Li Chen   +5 more
wiley   +1 more source

Steroids for DOPed Applications: A Compiler for Automated Data-Oriented Programming [PDF]

open access: yesarXiv, 2020
The wide-spread adoption of system defenses such as the randomization of code, stack, and heap raises the bar for code-reuse attacks. Thus, attackers utilize a scripting engine in target programs like a web browser to prepare the code-reuse chain, e.g., relocate gadget addresses or perform a just-in-time gadget search.
arxiv  

Light Quantity Impacts Early Response to Cold and Cold Acclimation in Young Leaves of Arabidopsis

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Plant reactions to stress vary with development stage and fitness. This study assessed the relationship between light and chilling stress in Arabidopsis acclimation. By analysing the transcriptome and proteome responses of expanding leaves subjected to varying light intensity and cold, 2251 and 2064 early response genes and proteins were ...
Markéta Luklová   +14 more
wiley   +1 more source

Occurence of active layer optical properties on some Lasing characteristics dye-doped Ch LC [PDF]

open access: yesarXiv, 2010
Effect of a planar texture quality and its thickness on lasing spectrums and thresholds in dye-doped cholesteric liquid crystal (CLC) of steroid type is explored. Transition from the qualitative planar texture to the poor texture quality is accompanied by change of characteristic mode structures and by shift of barycentre in the long-wave side and the ...
arxiv  

Gut Microbiota Dysbiosis: Pathogenesis, Diseases, Prevention, and Therapy

open access: yesMedComm, Volume 6, Issue 5, May 2025.
ABSTRACT Dysbiosis refers to the disruption of the gut microbiota balance and is the pathological basis of various diseases. The main pathogenic mechanisms include impaired intestinal mucosal barrier function, inflammation activation, immune dysregulation, and metabolic abnormalities.
Yao Shen   +5 more
wiley   +1 more source

Natural products targeting tumour angiogenesis

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 10, Page 2094-2136, May 2025.
Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu   +2 more
wiley   +1 more source

Aqueous solution interactions with sex hormone-binding globulin and estradiol: A theoretical investigation [PDF]

open access: yesarXiv, 2017
Sex hormone-binding globulin (SHBG) is a binding protein that regulates availability of steroids hormones in the plasma. Although best known as steroid carrier, studies have associated SHBG in modulating behavioral aspects related to sexual receptivity.
arxiv  

Characterisation of neurogenic lipolytic responses in white adipose tissue ex vivo

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 9, Page 1975-1988, May 2025.
Background and Purpose Dysfunction of the autonomic nervous system is associated with cardiovascular dysfunction, including metabolic syndrome and obesity. Understanding mechanisms of neurogenic control of white adipose tissue is key to understanding adipose physiology and pathophysiology, though there is limited research exploring this in adipose ...
Kayleigh E. Goddard, Samuel J. Fountain
wiley   +1 more source

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