Results 51 to 60 of about 3,096 (185)
, 2016 The steroid hydroxylases CYP17A1 (P450c17, 17-hydroxylase/17,20-lyase) and CYP21A2 (P450c21, 21-hydroxylase) catalyze progesterone hydroxylation at one or more sites within a 2 Å radius.
Yishan Zhou (2046052) +7 more
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The Plant Genome, Volume 19, Issue 2, June 2026.Abstract The genus Citrus is characterized by a reticulate evolutionary history with frequent hybridization, making it an intriguing subject for genome evolution investigation. Citrus changshan‐huyou Y. B. Chang (Huyou) is a unique landrace first discovered in Zhejiang Province, China, with premium fruit quality.
Zhanghui Zeng +14 more
wiley +1 more source
, 2018 Steroidal drugs are widely used for anti-inflammation, anti-tumor action, endocrine regulation, and fertility management, among other uses.
Li-Qin Xu +7 more
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The FEBS Journal, Volume 293, Issue 11, Page 3140-3165, June 2026.Intra‐tumoral oxygen deprivation (hypoxia) promotes the activation of hypoxia‐inducible factors (HIFs) that orchestrate the transcriptional adaptation of cancer cells to hypoxia. Hypoxia is prevalent in hepatocellular carcinoma (HCC), a cancer type with limited therapeutic options.
Ioanna‐Maria Gkotinakou +6 more
wiley +1 more source
Rethinking the role of HIF in hepatocellular carcinoma
The FEBS Journal, Volume 293, Issue 11, Page 3131-3134, June 2026.Tumor hypoxia is a hallmark of cancer driving disease, in part through activation of hypoxia‐inducible factors (HIFs). While HIF‐1α is classically understood as a hypoxia‐responsive transcription factor, its role under normoxic conditions in cells is less clear.
Niall S. Kenneth +2 more
wiley +1 more source
Chemical suppression of steroidogenesis.
, 1981 A large number of chemicals are known to interfere with steroidogenesis in the adrenal cortex and other tissues. Many xenobiotics inhibit steroid hormone production as a result of interactions with cytochrome P-450-containing hydroxylases in adrenal ...
Colby, H D
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Journal of Neurochemistry, Volume 170, Issue 6, June 2026.Schematic representation of a large dense‐core vesicle in PC12 cells highlighting its main molecular organization. The diagram illustrates the presence of membrane transporters, proton pumps and intravesicular matrix proteins that establish the electrochemical gradients required for neurotransmitter uptake, vesicle acidification and efficient storage ...
Noemi Socas‐Pérez +2 more
wiley +1 more source
, 2016 Biosynthesis of steroid hormones in vertebrates involves three cytochrome P450 hydroxylases, CYP11A1, CYP17A1 and CYP19A1, which catalyze sequential steps in steroidogenesis.
David Lamb
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Studies on steroid hydroxylations in the adrenal cortex [PDF]
, 1972 Methods were developed for the preparation of large quantities of bovine adrenal cortex mitochondria. Adrenodoxin and adrenodoxin reductase, two components of the steroid hydroxylases found in these mitochondria, were isolated and examined.
Wickramasinghe, R.H.
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16 p.-7 fig.-2 tab.Testosterone holds significant medical and economic importance, with the global market for testosterone replacement therapies valued at approximately $1.9 billion in 2023.
Getino, Luis +6 more
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