Results 81 to 90 of about 3,096 (185)

Minor activities and transition state properties of the human steroid hydroxylases cytochromes P450c17 and P450c21, from reactions observed with deuterium-labeled substrates. [PDF]

Biochemistry, 2012
Yoshimoto FK, Zhou Y, Peng HM, Stidd D, Yoshimoto JA, Sharma KK, Matthew S, Auchus RJ.   +7 more
europepmc   +1 more source

The Expression of Placental 17β-Hydroxysteroid Dehydrogenase Genes Is Associated with the Elevation of Active Androgens and Estrogens in Pregnant Women, but Does Not Affect 11-Oxygenated C19 Steroids. [PDF]

Int J Mol Sci
Yokohama Y, Watanabe Y, Nakajima KI, Umezawa A, Takahashi S, Mori Y, Kato Y, Kawabe JI, Yazawa T.   +8 more
europepmc   +1 more source

A Synthetic Molybdenum Hydroxylase Compound That Cleaves C-H Bonds by Hydride Abstraction. [PDF]

J Am Chem Soc
Modappilappally AV, Mankad NP.
europepmc   +1 more source

Whole-genomic and transcriptomic analyses elucidate <i>p</i>-cresol and styrene degradation metabolism in <i>Rhodococcus opacus</i> 1CP. [PDF]

Appl Environ Microbiol
Kumaran S, Heine T, Gröning JAD, Schlömann M, Albersmeier A, Busche T, Kalinowski J, Rückert-Reed C, Schaffert L, Tischler D.   +9 more
europepmc   +1 more source

Studies on Adrenal Steroid Hydroxylases

Journal of Biological Chemistry, 1971
Tokuji Kimura, Yoshio Nagata, Jitsuo Tsurugi   +2 more
openaire   +1 more source

Steroid hydroxylases

, 2000
Jong, Frank
core   +1 more source

The duration of induction and species influences the downregulation of cytochrome P450 by the interferon inducer polyinosinic acid-polycytidylic acid

, 1995
Interferon (IFN) has long been recognized to downregulate cytochrome P450-mediated drug metabolism. Some investigations have shown that induced P450 enzymes tend to be more resistant to the depressant effect of IFN, whereas constitutive forms of P450 are

core  

Dexamethasone regulates gene expression in chondrocytes through MKP-1 and downregulates cholesterol hydroxylases CH25H and CYP7B1. [PDF]

Inflamm Res
Lehtola T, Pemmari A, Nummenmaa E, Valjus I, Hämäläinen M, Moilanen T, Vuolteenaho K, Moilanen E.   +7 more
europepmc   +1 more source

P450 engineering via structure-guided rational design achieves high C21-selectivity and bioconversion in steroid biosynthesis. [PDF]

Synth Syst Biotechnol
Yang J, Li R, Gao Q, Ma L, Wang Q, Ma G, Fan Y, Li S, Xu LH.   +8 more
europepmc   +1 more source

New Mechanistic Evidence for Perfluorodecanoic Acid (PFDA) Teratogenicity via CYP26A1-Mediated Retinoic Acid Metabolism and Signaling. [PDF]

Chem Res Toxicol
Hvizdak M, Kandel SE, Lampe JN.
europepmc   +1 more source