Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinant Human Enzyme [PDF]
Tilman U. Hutschenreuter +2 more
openalex +1 more source
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
Effectiveness of epidural steroid injection in the management of lumbar prolapsed intervertebral disc using interlaminar and transforaminal route [PDF]
Eswara Reddy G +2 more
openalex +1 more source
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han +9 more
wiley +1 more source
Accurate non‐invasive diagnosis and staging of non‐alcoholic fatty liver disease using the urinary steroid metabolome [PDF]
Ahmad Moolla +20 more
openalex +1 more source
Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang +7 more
wiley +1 more source
Small but serious risk of perioperative steroid use [PDF]
Tae-Yop Kim
doaj +1 more source
POS0472 TREATMENT RESPONSE TO INTRAMUSCULAR STEROIDS IN PATIENTS LIVING WITH RHEUMATOID ARTHRITIS: AN EXPLORATORY ANALYSIS USING TRACKED DAILY SYMPTOMS [PDF]
Mariam Al-Attar +3 more
openalex +1 more source

