Results 11 to 20 of about 729,000 (364)

Dissociated Steroids [PDF]

The Scientific World Journal, 2007
Glucocorticoids (GCs) are some of the most important drugs in clinical use today. They are mainly used to suppress disease-related inflammation and are widely used for the treatment of many inflammatory diseases including asthma and arthritis.
Matthew C. Catley
doaj   +3 more sources

Supergenes on Steroids

Philosophical Transactions of the Royal Society B: Biological Sciences, 2021
At the birth of supergenes, the genomic landscape is dramatically re-organized leading to pronounced differences in phenotypes and increased intrasexual diversity. Two of the best-studied supergenes in vertebrates are arguably the inversion polymorphisms on chromosomes 2 and 11 in the white-throated sparrow ( Zonotrichia ...
Küpper, Clemens, Maney, Donna
openaire   +4 more sources

Steroid Stewardship

Indian Journal of Endocrinology and Metabolism, 2022
Steroid stewardship is the systematic effort to prescribe and monitor glucocorticoids in a rational manner, while balancing benefit and potential risk, in patients who require this therapy. Steroid stewardship includes pre-prescription screening, rational prescription, medical care during corticosteroid use, and appropriate monitoring after ...
Sanjay Kalra, Ashok Kumar, Rakesh Sahay
openaire   +3 more sources

Results of pancreas transplantation after steroid withdrawal under tacrolimus immunosuppression [PDF]

, 2000
Purpose. The results of steroid withdrawal in pancreas transplant recipients under tacrolimus immunosuppression were analyzed. Methods. From July 4, 1994 until April 30, 1998, 147 pancreas transplantations were performed in 141 patients, including 126 ...
Burke, Carlos A. Vivas, Corry, Corry, Corry, Fioretto, Foger, Grewal, Gritsch, Hricik, Hricik, Hricik, Ingulli, John J. Fung, Jordan, Jordan, Kaufman, Landgraf, Mark L. Jordan, Mayer, Mazariegos, McKee, Patrick Luke, Pirsch, Pradip Chakrabarti, Robert J. Corry, Ron Shapiro, Scantlebury, Schulak, Schulak, Shapiro, Shapiro, Shapiro, Shapiro, Solders, Sollinger, Stratta, Stratta, Sugitani, Thaysen, Thomas E. Starzl, Tyden, Velma P. Scantlebury   +42 more
core   +1 more source

Steroid induced osteonecrosis: An analysis of steroid dosing risk. [PDF]

, 2010
Osteonecrosis is a serious condition involving bone destruction that frequently requires surgical treatment to rebuild the joint. While there is an abundance of literature documenting corticosteroid related osteonecrosis, there is no consensus as to the ...
Chang, Christopher, Cheema, Gurtej, Gershwin, M Eric, Naguwa, Stanley M, Powell, Christian   +4 more
core   +1 more source

Realising the therapeutic potential of neuroactive steroid modulators of the GABA_A receptor [PDF]

, 2020
In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR).
Belelli, Delia, Gee, Kelvin W., Hogenkamp, Derk, Lambert, Jeremy J.   +3 more
core   +1 more source

Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]

, 2006
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Akwa Y, Baghai TC, Baker ER, Barrett-Connor E, Bicikova M, Bitran D, Bloch M, Brambilla F, Brambilla F, Brambilla F, Cornelius Schüle, Crawley JN, Dalton K, Daniela Eser, Dennerstein L, Dong E, Elena Romeo, Eser D, Evans RM, Fabian TJ, Freeman E, Freeman EW, Friess E, George MS, Goodyer IM, Guidotti A, Heydari B, Heydary B, Kita A, Koszycki D, Lawrie TA, Maayan R, Magill PJ, Majewska MD, Majewska MD, Majewska MD, Matsumoto K, Meieran SE, Melchior CL, Melchior CL, Mensah-Nyagan AG, Mienville JM, Monnet FP, Padberg F, Papadopoulos V, Paul SM, Purdy RH, Rainer Rupprecht, Reddy DS, Reddy DS, Reddy DS, Rodgers RJ, Romeo E, Rupprecht R, Rupprecht R, Schmidt PJ, Schule C, Schule C, Semeniuk T, Serra M, Serra M, Strohle A, Strohle A, Strohle A, Strous RD, Takebayashi M, Thomas C. Baghai, Tollefson GD, Trauger JW, Urani A, Uzunov DP, Uzunova V, Uzunova V, Uzunova V, Vanselow W, Wieland S, Wolkowitz OM, Wolkowitz OM, Wu FS, Zwanzger P   +79 more
core   +1 more source

Pericarditis in contemporary therapeutic clinic: nosological spectrum, approaches to diagnosis and treatment

Терапевтический архив, 2020
Aim.To analyze the register of pericarditis in a therapeutic clinic, to evaluate their nosological spectrum, to optimize approaches to diagnosis and treatment.
O. V. Blagova, A. V. Nedostup, V. P. Sedov, E. A. Kogan, I. N. Alijeva, G. Yu. Sorokin, N. D. Sarkisova   +6 more
doaj   +1 more source

Systemic steroid administration combined with intratympanic steroid injection in the treatment of a unilateral sudden hearing loss prognosis prediction model: A retrospective observational study

Frontiers in Neurology, 2022
Idiopathic sudden sensorineural hearing loss (ISSNHL) is an emergency ear disease that is referred to as a sensorineural hearing loss of at least 30 dB in three sequential frequencies and occurs over a period of < 72 h.
Hao Yuan, Cheng-Cheng Liu, Peng-Wei Ma, Jia-Wei Chen, Wei-Long Wang, Wei Gao, Pei-Heng Lu, Xue-Rui Ding, Yu-Qiang Lun, Lian-Jun Lu   +9 more
doaj   +1 more source

Clinical trial of FK 506 immunosuppression in adult cardiac transplantation [PDF]

, 1992
The new immunosuppressive agent FK 506 was used as primary immunotherapy in conjunction with low-dose steroids and azathioprine in 72 patients subsequent to orthotopic cardiac transplantation.
Armitage, Bartley P. Griffith, Billingham, Dew, Fung, Gary C. Marrone, John Fung, John M. Armitage, Kormos, Kusne, Robert L. Hardesty, Robert L. Kormos, Shigeki Morita, Starzl, Starzl, Tamura, Thomas E. Starzl, Todo   +17 more
core   +1 more source