Results 201 to 210 of about 437,081 (334)

Studies of the Microbiological Oxidation of Steroids by Cunninghamella blakesleeana H-334 [PDF]

open access: gold, 1955
Kingsley M. Mann   +5 more
openalex   +1 more source

Distinct Alterations of Inflammatory Biomarkers in Cluster Headache: A Case Control Study

open access: yesAnnals of Neurology, EarlyView.
Objective Investigate the immune system's role in cluster headache by analyzing cytokines in people with cluster headache and headache‐free controls, and explore if certain cytokines could predict a specific phenotype. Methods We measured 45 cytokines in adult participants from the Danish Cluster Headache Biobank in a prospective case–control setup ...
Nunu Laura Timotheussen Lund   +6 more
wiley   +1 more source

A Sequential Release Micro‐nano System for Colitis Therapy via Gut Microbiota and Immune Regulation

open access: yesAngewandte Chemie, EarlyView.
The micro‐nano system achieves the sequential release of drugs in response to gut microbiota and reactive oxygen species (ROS). Inulin prebiotics restore gut microbiota balance. Selenium compounds scavenge ROS and promote macrophage polarization, while 3‐oxolithocholic acid suppresses TH17‐cell differentiation. As a multifactorial therapeutic approach,
Dongdong Zhu   +9 more
wiley   +2 more sources

Anticancer Activities of Natural and Synthetic Steroids: A Review. [PDF]

open access: yesACS Omega
Mendoza Lara DF   +4 more
europepmc   +1 more source

Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features

open access: yesAnnals of Neurology, EarlyView.
Objectives We analyzed the genotypic and phenotypic features of patients with psychosis of epilepsy (POE). Methods Patients with POE recruited to an epilepsy genetics research program underwent phenotyping and genetic analysis. The latter included screening for rare pathogenic variants in epilepsy genes, and polygenic risk score (PRS) calculation for ...
Genevieve Rayner   +4 more
wiley   +1 more source

Mapping Molecular Pathways of Multiple Sclerosis: A Gene Prioritization and Network Analysis of White Matter Pathology Transcriptomics

open access: yesAnnals of Neurology, EarlyView.
Objectives Rapid advances in transcriptomics have driven efforts to identify deregulated pathways in multiple sclerosis (MS) tissues, though many detected differentially expressed genes are likely false positives, with only a small fraction reflecting actual pathological events. Robust, integrative methods are essential for accurately understanding the
Gianmarco Abbadessa   +11 more
wiley   +1 more source

Site‐Selective C─H Bond Functionalization of Sugars

open access: yesAngewandte Chemie, EarlyView.
Nontypical sugars represent a prominent, yet hardly, accessible class of biologically‐active compounds. Here, we disclose a technology toward non‐typical sugars that allows facile, and site‐selective functionalization of native sugars. The protocol is compatible with a variety of unprotected carbohydrates featuring sensitive aglycons and a diverse set ...
Elena V. Stepanova   +4 more
wiley   +2 more sources

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