Results 211 to 220 of about 752,763 (369)

Two Doses of Daclizumab in Conjunction with Low‐Dose Cyclosporine, Mycophenolate Mofetil and Steroids Resulted in a Low Incidence of Acute Rejection after Renal Transplantation [PDF]

, 2003
Henrik Ekberg, Nils H. Persson, Ragnar Källén, N. Gül‐Baykurt   +3 more
openalex   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

A systematic review of therapeutic options for lymphocytic esophagitis. [PDF]

Dis Esophagus
Nguyen B, Cheng CF, Jowhari F.
europepmc   +1 more source

Steroid effects on intracellular degradation of insulin and crinophagy in isolated pancreatic islets

, 2007
Monica Sandberg, Lisa Borg
openalex   +2 more sources

Hormetic Property of Ginseng Steroids on Anti-Oxidant Status against Exercise Challenge in Rat Skeletal Muscle [PDF]

, 2017
Ming-Fen Hsu, Szu-Hsien Yu, Mallikarjuna Korivi, Wei-Horng Jean, Shin‐Da Lee, Chih‐Yang Huang, Yi-Hung Liao, Jessica Bo Li Lu, Chia‐Hua Kuo   +8 more
openalex   +1 more source

A Modular Chemoenzymatic Cascade Simplifies Divergent Synthesis of Natural and Unnatural Benzylisoquinoline Alkaloids

Advanced Science, EarlyView.
A simplified chemoenzymatic platform is designed to integrate an enzyme cascade with subsequent chemical steps, enabling the divergent production of diverse benzylisoquinoline alkaloids (BIAs). Demonstrating remarkable versatility and enantioselectivity, four distinct classes of BIAs are efficiently generated, in which the natural medicine papaverine ...
Huiling Liu, Zhenbo Yuan, Yue Gao, Fei Li, Zhiwei Deng, Yan Zhang, Zhengshan Luo, Changmei Liu, Yijian Rao   +8 more
wiley   +1 more source

Divergent evolution of fungal P450 monooxygenase unlocks simultaneous access to C12β and C15α oxyfunctionalization of steroids. [PDF]

Nat Commun
Wang L, Wang Y, Peng X, Gao C, Wei X, Chen P, Xiao P, Li Q, Li A.   +8 more
europepmc   +1 more source

Effect of combined hormonal and insulin therapy on the steroid hormone receptors and growth factors signalling in diabetic mice prostate

, 2010
Wagner José Fávaro, Valéria Helena Alves Cagnon   +1 more
openalex   +2 more sources

CSI on steroids [PDF]

, 2015
Howard Wolinsky
openalex   +1 more source

Arid1a Deficiency Drives Aristolochic Acid‐Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair

Advanced Science, EarlyView.
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang, Shi‐Hao Bai, Shu‐Jin Song, Xiao‐Li Zhang, Xue‐Ying Shang, Zhao‐Ning Lu, Xiao‐Fang Cui, Xin‐Le Zhu, Ze‐Guang Han   +8 more
wiley   +1 more source