Results 51 to 60 of about 398,765 (315)

Pregnane steroids from a gorgonian coral Subergorgia suberosa with anti-flu virus effects

, 2016
Five new pregnane-type steroids namely subergorgols T-X (1-5) and three known analogues (6-8) were isolated from a gorgonian coral Subergorgia suberosa.
Ren, Jinwei, Lin, Wenhan, Cheng, Wei, Huang, Qixi, Liu, Huagang, Zhang, Liangren, van Ofwegen, Leen, Long, Hailin, Jin, Hongwei   +8 more
core   +1 more source

Validation of a fast LC-MS/MS method for the analysis of bisphenol A (BPA) and urethane dimethacrylate (UDMA) in eluates of dental polymer-based materials

Scientific Reports
Polymer-based materials are widely used in dentistry. However, concerns exist regarding their biocompatibility because monomers such as urethane dimethacrylate (UDMA) and bisphenol A (BPA) may leach from the materials and affect the immune and endocrine ...
Jana Vitku, Tereza Skodova, Ye Eun Tak, Babak Sayahpour, Sarah Bühling, Tereza Srolerova, Lucie Kolatorova, Anezka Varausova, Antonin Tichy   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The impact of nandrolone decanoate and growth hormone on biosynthesis of steroids in rats

, 2013
Growth hormone (GH) and anabolic androgenic steroids (AAS) are commonly used in sports communities. Several studies have suggested an association between GH and AAS.
Johansson, Jenny,, Grönbladh, Alfhild,, Hallberg, Mathias,, Kushnir, Mark M,, Bergquist, Jonas,   +4 more
core   +1 more source

Bismuth(III) Reagents in Steroid and Terpene Chemistry

Molecules, 2011
Steroid and terpene chemistry still have a great impact on medicinal chemistry. Therefore, the development of new reactions or “greener” processes in this field is a contemporaneous issue.
Jorge A. R. Salvador, Rui M. A. Pinto, Samuel M. Silvestre   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Risk factors for fragility fractures in patients with immunobullous diseases on long-term systemic glucocorticoids

Dermatology Reports
Dear Editor, Systemic glucocorticoids remain a cornerstone of therapy in immunobullous diseases. Yet little is known about glucocorticoid induced osteoporosis (GIOP) in patients with immunobullous diseases. We performed a retrospective review of medical
MeiQi May Liau, Nisha Suyien Chandran
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis [PDF]

, 2014
T helper 2 (Th2) cells regulate helminth infections, allergic disorders, tumor immunity, and pregnancy by secreting various cytokines. It is likely that there are undiscovered Th2 signaling molecules.
Xiuwei Zhang, Sarah A. Teichmann, Zhang, Xiuwei, Dingler, Felix A., Felix A. Dingler, Teichmann, Sarah A., Valentina Proserpio, Berthold Göttgens, Dingler, Felix A, Kolodziejczyk, Aleksandra A, Teichmann, Sarah A, Proserpio, V, Taylor, Angela E., Hebenstreit, Daniel, Taylor, Angela E; id_orcid, Proserpio, Valentina, Haim-Vilmovsky, Liora, McKenzie, Andrew N J, Liora Haim-Vilmovsky, Göttgens, Berthold, Andrew N.J. McKenzie, Arlt, Wiebke, Angela E. Taylor, McKenzie, Andrew N.J., Daniel Hebenstreit, Kolodziejczyk, Aleksandra A., Aleksandra A. Kolodziejczyk, Wiebke Arlt, Victoria Moignard, Moignard, Victoria, McKenzie, Andrew N. J., Bidesh Mahata, Mahata, Bidesh   +32 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source