Results 91 to 100 of about 2,244,421 (182)

Phase 1 dose escalation and expansion trial of the bispecific CD47 inhibitor and CD40 agonist Fc‐fusion protein SL‐172154 (SIRPα‐Fc‐CD40L) in patients with higher‐risk myelodysplastic syndrome or acute myeloid leukemia

open access: yesCancer, Volume 132, Issue 19, 1 October 2026.
Abstract Background This clinical trial sought to determine whether SL‐172154 could be combined safely and improve the efficacy of azacitidine (AZA) in patients with higher‐risk myelodysplastic syndrome (HR‐MDS) or acute myeloid leukemia (AML). Methods Dose escalation: doses of 1, 3, and 6 mg/kg SL‐172154 was evaluated as monotherapy or in combination ...
Naval G. Daver   +24 more
wiley   +1 more source

Síndrome de Stevens-Johnson y necrólisis epidérmica tóxica [PDF]

open access: yes, 2019
Stevens-Johnson syndrome and toxic epidermal necrolisis are severe skin drug reactions that form part of the same entity. Despite its low frequency, they are associated with high morbidity and mortality rates.
Mejía, Milton   +2 more
core  

Chlordiazepoxide-induced Stevens-Johnson Syndrome [PDF]

open access: yes, 2005
The causes of Stevens-Johnson syndrome (SJS) can be categorized as iatrogenic, infectious or idiopathic. Drug-induced SJS is associated with various antibiotics, anticonvulsants, and other drugs. However, no previous reports have mentioned an association
Huang, Po-Hsun, Tsai, Wei-Jen
core   +1 more source

Adverse Reactions Identified after Approval of Novel Medicines: Analysis of 339 New Molecular Entities and Therapeutic Biologics

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1120-1128, October 2026.
Postmarketing safety surveillance data identify safety issues not identified in preapproval clinical trials. We describe the frequency of new safety issues overall and by labeling section and the relationship of the most commonly added safety issues with the cumulative number of prescriptions dispensed via retail pharmacies.
Ellen Pinnow   +14 more
wiley   +1 more source

A Post–NGP Mitsuokella jalaludinii as a Therapeutic Candidate for Gout

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Schematic summary of the therapeutic mechanisms and evaluation of the post–NGP strain M. jalaludinii PMC73 for gout. PMC73 demonstrated uric acid–lowering efficacy through purine catabolism and hypoxanthine utilization, along with intracellular uric acid reduction in macrophages.
Mohammed Solayman Hossain   +13 more
wiley   +1 more source

Stevens-Johnson syndrome is an immune catastrophe [PDF]

open access: yes, 2019
Stevens-Johnson syndrome is an immune catastrophe S.I. Bardenikova1, O.S. Pentkovskaya2, E.K. Isaeva2 1 Moscow State University of Medicine and Dentistry named after A.I.
E.K. Isaeva
core  

Cocaine-related Stevens-Johnson syndrome.

open access: yes, 2000
We report the case of a 26-year-old student with erosive skin changes on his oral and genital mucosa and skin as well as on his thighs twice after cocaine snorting.
Hofbauer GF, Nestle FO, Burg G
core   +1 more source

Study of Stevens - Johnson syndrome [PDF]

open access: yes, 2018
Stevens-Johnson Syndrome is uncommon and consequential disease which affects the specific organs like the skin, mucous membrane, genitals, and eyes. Stevens-Johnson syndrome and Toxic epidermal necrolysis both are compatible and correlate with erythema ...
Shaik.Sartaj, Aravind Swamy
core   +1 more source

Squills vs. Hyacinths – A revised genus delimitation in Hyacinthinae (Hyacintheae, Scilloideae, Asparagaceae) based on phylogenomics

open access: yesTAXON, Volume 75, Issue 5, October 2026.
Abstract Scilla s.l. (Asparagaceae: Scilloideae) represents a notable Mediterranean geophyte radiation, yet genus delimitation in subtribe Hyacinthinae has long suffered from inconsistent and conflicting generic concepts. A limited set of informative morphological characters and recurrent shifts in circumscription have repeatedly hindered progress ...
Tim Böhnert   +6 more
wiley   +1 more source

Stevens Johnson Syndrome induced by a combination of lamotrigine and valproic acid in a patient with bipolar disorder: A case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Stevens Johnson syndrome is a severe and potentially lifethreatening cutaneous reaction associated with lamotrigine. The incidence of developing Steven- Johnson syndrome during lamotrigine therapy is low.
Uğur Öner, Julide Güler, Elif Yılmaz
doaj  

Home - About - Disclaimer - Privacy