Results 51 to 60 of about 17,732 (155)

Coronavirus-disease-2019-associated Stevens–Johnsons syndrome in a 15-year-old boy: a case report and review of the literature

Journal of Medical Case Reports
Background Stevens–Johnson syndrome (SJS) is a life-threatening condition characterized by high fever and severe mucocutaneous lesions, often triggered by drugs or infection.
Na Li, Jian Li
doaj   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

Contact Dermatitis, EarlyView.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti, Francesco Catamerò, Giulia Liccioli, Leonardo Tomei, Simona Barni, Mattia Giovannini, Lucrezia Sarti, Francesca Mori   +7 more
wiley   +1 more source

Amitriptyline Induced Life‐Threatening Steven–Johnson Syndrome: Case Report

Clinical Case Reports
Stevens–Johnson syndrome is one of the few dermatological emergencies in clinical practice. The syndrome is often secondary to the usage of drugs, of which allopurinol, penicillins, sulfa drugs, ibuprofen, sodium valproate, phenytoin, lamotrigine, and ...
Wondwosen Mengist Dereje, Lidya Yalew, Nardos Tafesse, Teklegiorgis Goshime Getachew   +3 more
doaj   +1 more source

Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He, Shaymaa Hegazy, Phyu P. Aung, Priyadharsini Nagarajan, Fiorinda Muhaj, Adrienne N. Choksi, Ana M. Ciurea, Kelly C. Nelson, Doina Ivan, Carlos A. Torres‐ Cabala, Victor G. Prieto, Jonathan L. Curry   +11 more
wiley   +1 more source

Risk of Stevens-Johnson Syndrome with AEDs

Pediatric Neurology Briefs, 1995
An international case-controlled study of medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis is reported by the Groupe Epidemiologie LY Stevens Johnson (ELYS), Department of Dermatology, and Department of Public Health,
J Gordon Millichap
doaj   +1 more source

The Accuracy of Frozen Section Histopathology in the Rapid Diagnosis of Severe Cutaneous Adverse Reactions: A Systematic Review and Meta‐Analysis

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Frozen section analysis enables rapid diagnosis, but its diagnostic accuracy in the setting of severe cutaneous adverse reactions (SCARs) remains poorly defined. Methods A systematic review and meta‐analysis were performed to evaluate the diagnostic performance of frozen sections in the rapid identification of SCARs, with a focus on
Cody C. Frear, Louise Frear, Duncan Lambie, Amanda Godbolt   +3 more
wiley   +1 more source

POST OPERATIVE STEVEN JOHNSON TYPE REACTION SECONDARY TO PIPERACILLIN

Pakistan Armed Forces Medical Journal, 2019
Toxic epidermal necrolysis (TEN) and Stevens–Johnson syndrome (SJS) are lethal cutaneous reactions to medications stirring1–2 per million individuals every year.
Dr. Anam Liaqat, Dr. Muhammad Waseem, Dr. Muhammad Asad   +2 more
doaj   +2 more sources

Effect and length of doxycycline administration in elderly patients with bullous pemphigoid

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Bullous pemphigoid (BP) is the most common autoimmune blistering disease and primarily affects the elderly. Systemic corticosteroids and immunosuppressive drugs are the standard treatment, but side effects often restrict their use. Doxycycline has been proposed as an alternative, but there is limited long‐term, real‐world data on its
Alena Merkel‐Ropele, Wolfgang Salmhofer, Peter Wolf   +2 more
wiley   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Stevens-Johnson Syndrome and Erythema Multiforme Induced by Imiquimod 5% Cream

Dermatology Practical & Conceptual
Introduction: Topical imiquimod is a safe and effective treatment for actinic keratoses, superficial basal cell carcinomas and anogenital warts. The treatment is commonly associated with local inflammatory reactions, while systemic side effects are rare
Ilaria Salvi, Ilaria Trave, Riccardo Castelli, Aurora Parodi, Emanuele Cozzani   +4 more
doaj   +1 more source