Results 91 to 100 of about 2,224,728 (196)
Optimizing neoadjuvant therapy for muscle‐invasive bladder cancer patients who are eligible for cisplatin remains difficult, owing particularly to high toxicity and recurrence rates. This meta‐analysis compared dose‐dense methotrexate, vinblastine, doxorubicin, and cisplatin (ddMVAC) against durvalumab plus gemcitabine‐cisplatin (D‐GC) and GC alone ...
Maurin Helen Mangold +12 more
wiley +1 more source
Postmarketing safety surveillance data identify safety issues not identified in preapproval clinical trials. We describe the frequency of new safety issues overall and by labeling section and the relationship of the most commonly added safety issues with the cumulative number of prescriptions dispensed via retail pharmacies.
Ellen Pinnow +14 more
wiley +1 more source
Mycoplasma pneumoniae induced Stevens-Johnson syndrome [PDF]
Stevens-Johnsonov sindrom (SJS) je teška bolest kože i sluznica karakterizirana target (iris) lezijama i nekrozom epidermisa kao posljedica reakcije preosjetljivosti potaknute lijekovima, infektivnim uzročnicima ili malignomima.
Pavić, Ivica +9 more
core +1 more source
Stevens Johnson syndrome is a severe and potentially lifethreatening cutaneous reaction associated with lamotrigine. The incidence of developing Steven- Johnson syndrome during lamotrigine therapy is low.
Uğur Öner, Julide Güler, Elif Yılmaz
doaj
Evaluation of conjunctival bacterial flora in patients with Stevens-Johnson Syndrome
OBJECTIVE: To determine the conjunctival bacterial flora present in patients with Stevens-Johnson syndrome. METHODS: A prospective study of the conjunctival bacterial flora was performed in 41 eyes of 22 patients with Stevens-Johnson syndrome.
Luciana Frizon +6 more
doaj +1 more source
A Post–NGP Mitsuokella jalaludinii as a Therapeutic Candidate for Gout
Schematic summary of the therapeutic mechanisms and evaluation of the post–NGP strain M. jalaludinii PMC73 for gout. PMC73 demonstrated uric acid–lowering efficacy through purine catabolism and hypoxanthine utilization, along with intracellular uric acid reduction in macrophages.
Mohammed Solayman Hossain +13 more
wiley +1 more source
Pathophysiology-Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis [PDF]
This poster examines recent research into genetic associations and emergent theories concerning the pathogenesis of Stevens-Johnson Syndrome and Toxic Epidermal ...
Klein, Douglas M.
core
INtraVESical immunoTherapy (INVEST) prior to radical cystectomy for bladder cancer: trial protocol
Background High‐risk non‐muscle‐invasive bladder cancer (HRNMIBC) has a variable prognosis, managed predominantly by local surgical resection and intravesical Bacillus Calmette–Guérin (BCG), or radical cystectomy (RC). Current treatments are poorly tolerated, have supply limitations and often fail to control the disease.
Ruby Lister‐Whelan +13 more
wiley +1 more source
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti +7 more
wiley +1 more source
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge +6 more
wiley +1 more source

