Results 91 to 100 of about 2,224,728 (196)

Indirect Comparison of Neoadjuvant Treatment Strategies for Muscle‐Invasive Bladder Cancer: ddMVAC and Perioperative Durvalumab‐Gemcitabine‐Cisplatin Versus Gemcitabine‐Cisplatin: A Systematic Review and Network Meta‐Analysis of Randomised Controlled Trials

open access: yesInternational Journal of Cancer, Volume 159, Issue 8, Page 1962-1973, 15 October 2026.
Optimizing neoadjuvant therapy for muscle‐invasive bladder cancer patients who are eligible for cisplatin remains difficult, owing particularly to high toxicity and recurrence rates. This meta‐analysis compared dose‐dense methotrexate, vinblastine, doxorubicin, and cisplatin (ddMVAC) against durvalumab plus gemcitabine‐cisplatin (D‐GC) and GC alone ...
Maurin Helen Mangold   +12 more
wiley   +1 more source

Adverse Reactions Identified after Approval of Novel Medicines: Analysis of 339 New Molecular Entities and Therapeutic Biologics

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1120-1128, October 2026.
Postmarketing safety surveillance data identify safety issues not identified in preapproval clinical trials. We describe the frequency of new safety issues overall and by labeling section and the relationship of the most commonly added safety issues with the cumulative number of prescriptions dispensed via retail pharmacies.
Ellen Pinnow   +14 more
wiley   +1 more source

Mycoplasma pneumoniae induced Stevens-Johnson syndrome [PDF]

open access: yes, 2009
Stevens-Johnsonov sindrom (SJS) je teška bolest kože i sluznica karakterizirana target (iris) lezijama i nekrozom epidermisa kao posljedica reakcije preosjetljivosti potaknute lijekovima, infektivnim uzročnicima ili malignomima.
Pavić, Ivica   +9 more
core   +1 more source

Stevens Johnson Syndrome induced by a combination of lamotrigine and valproic acid in a patient with bipolar disorder: A case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Stevens Johnson syndrome is a severe and potentially lifethreatening cutaneous reaction associated with lamotrigine. The incidence of developing Steven- Johnson syndrome during lamotrigine therapy is low.
Uğur Öner, Julide Güler, Elif Yılmaz
doaj  

Evaluation of conjunctival bacterial flora in patients with Stevens-Johnson Syndrome

open access: yesClinics, 2014
OBJECTIVE: To determine the conjunctival bacterial flora present in patients with Stevens-Johnson syndrome. METHODS: A prospective study of the conjunctival bacterial flora was performed in 41 eyes of 22 patients with Stevens-Johnson syndrome.
Luciana Frizon   +6 more
doaj   +1 more source

A Post–NGP Mitsuokella jalaludinii as a Therapeutic Candidate for Gout

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Schematic summary of the therapeutic mechanisms and evaluation of the post–NGP strain M. jalaludinii PMC73 for gout. PMC73 demonstrated uric acid–lowering efficacy through purine catabolism and hypoxanthine utilization, along with intracellular uric acid reduction in macrophages.
Mohammed Solayman Hossain   +13 more
wiley   +1 more source

Pathophysiology-Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis [PDF]

open access: yes, 2016
This poster examines recent research into genetic associations and emergent theories concerning the pathogenesis of Stevens-Johnson Syndrome and Toxic Epidermal ...
Klein, Douglas M.
core  

INtraVESical immunoTherapy (INVEST) prior to radical cystectomy for bladder cancer: trial protocol

open access: yesBJU International, Volume 138, Issue 4, Page 607-619, October 2026.
Background High‐risk non‐muscle‐invasive bladder cancer (HRNMIBC) has a variable prognosis, managed predominantly by local surgical resection and intravesical Bacillus Calmette–Guérin (BCG), or radical cystectomy (RC). Current treatments are poorly tolerated, have supply limitations and often fail to control the disease.
Ruby Lister‐Whelan   +13 more
wiley   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

open access: yesContact Dermatitis, Volume 95, Issue 4, Page 349-357, October 2026.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti   +7 more
wiley   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

open access: yesArthritis Care &Research, Volume 78, Issue 9, Page 1265-1269, September 2026.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy