Results 191 to 200 of about 2,491,702 (230)

Evaluation of combination therapy with etanercept and systemic corticosteroids for Stevens-Johnson syndrome and toxic epidermal necrolysis: A multicenter observational study.

Journal of Allergy and Clinical Immunology: In Practice, 2022
BACKGROUND Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) are fatal severe cutaneous adverse reactions, without consensus on the medical treatment. The use of systemic corticosteroids or intravenous immunoglobulin (IVIG) remains debatable.
Jing Zhang, Chun-Wei Lu, Chun-Bing Chen, Chuang-Wei Wang, Wei-Ti Chen, B. Cheng, Chao Ji, Weng-Hung Chung   +7 more
semanticscholar   +1 more source

Recognition and Management of Severe Cutaneous Adverse Drug Reactions (Including Drug Reaction with Eosinophilia and Systemic Symptoms, Stevens-Johnson Syndrome, and Toxic Epidermal Necrolysis).

The Medical clinics of North America, 2021
Severe cutaneous adverse reactions to medications (SCARs) include drug reaction with eosinophilia and systemic symptoms, Stevens-Johnson syndrome, toxic epidermal necrolysis, and acute generalized exanthematous pustulosis. They are all non-immunoglobulin
C. Owen, Jordan M. Jones
semanticscholar   +1 more source

Lid margin keratinization in Stevens-Johnson syndrome: Review of pathophysiology and histopathology.

The ocular surface, 2021
Lid margin keratinization (LMK) is a chronic ocular sequela of Stevens-Johnson syndrome (SJS), which causes lid wiper epitheliopathy and progressive ocular surface damage. The exact etiopathogenesis of LMK, however, remains elusive.
Swati Singh, Saumya Jakati, S. Shanbhag, A. Elhusseiny, A. Djalilian, S. Basu   +5 more
semanticscholar   +1 more source

Update on Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management

American Journal of Clinical Dermatology
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the most severe cutaneous adverse reactions that are typically drug-induced in adults. Both SJS and TEN have high morbidity and mortality rates.
Hemali Shah, Rose Parisi, E. Mukherjee, E. Phillips, R. Dodiuk-Gad   +4 more
semanticscholar   +1 more source

Lamotrigine and Stevens-Johnson Syndrome Prevention.

Psychopharmacology bulletin, 2021
Stevens-Johnson Syndrome (SJS) is a rare life-threatening condition characterized by severe mucocutaneous epidermal necrolysis and detachment of the epidermis.
Amber N. Edinoff, L. H. Nguyen, M. Fitz-Gerald, E. Crane, K. Lewis, S. S. Pierre, A. Kaye, A. Kaye, Jessica S. Kaye, Rachel J. Kaye, Sonja A. Gennuso, G. Varrassi, Omar Viswanath, Ivan Urits   +13 more
semanticscholar   +1 more source

Erythema multiforme, Stevens‐Johnson syndrome/toxic epidermal necrolysis – diagnosis and treatment

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2020
Prior to the first international consensus classification published in 1993, the clinical distinction between erythema multiforme (EM), Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) had been subject to uncertainty and controversy ...
P. Grünwald, M. Mockenhaupt, R. Panzer, S. Emmert   +3 more
semanticscholar   +1 more source

Biologic TNF-alpha inhibitors in the treatment of Stevens-Johnson syndrome and toxic epidermal necrolysis: a systemic review

Journal of dermatological treatment (Print), 2020
Background: Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) is one of severe cutaneous adverse reactions with low morbidity but high mortality.
Shan Zhang, Shunli Tang, Sheng Li, Yunlei Pan, Ying-guo Ding   +4 more
semanticscholar   +1 more source

Systemic therapies for Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: a SCORTEN‐based systematic review and meta‐analysis

Journal of the European Academy of Dermatology and Venereology, 2020
The SCORTEN score is a specific predictor of mortality for patients with Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN). There is little evidence in support of the common immunomodulating therapies for SJS/TEN.
I. Torres‐Navarro, Álvaro Briz-Redón, R. Botella‐Estrada, R. Botella‐Estrada   +3 more
semanticscholar   +1 more source

The nationwide epidemiological survey of Stevens-Johnson syndrome and toxic epidermal necrolysis in Japan, 2016-2018.

Journal of dermatological science (Amsterdam), 2020
BACKGROUND Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening severe cutaneous adverse reactions (SCARs). The first national epidemiological survey of SJS/TEN was carried out in 2008.
Yuma Sunaga, M. Kurosawa, Hirotaka Ochiai, Hideaki Watanabe, H. Sueki, H. Azukizawa, H. Asada, Y. Watanabe, Y. Yamaguchi, M. Aihara, Y. Mizukawa, M. Ohyama, N. Hama, R. Abe, H. Hashizume, Saeko Nakajima, T. Nomura, K. Kabashima, M. Tohyama, Hayato Takahashi, H. Mieno, M. Ueta, C. Sotozono, H. Niihara, E. Morita, A. Kokaze   +25 more
semanticscholar   +1 more source