Results 51 to 60 of about 2,491,702 (230)

Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans

Clinical Pharmacology &Therapeutics, EarlyView.
Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley   +1 more source

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures

Advances in Therapy, 2017
IntroductionStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic conditions occurring in the inpatient setting. There is a lack of consensus regarding appropriate management of SJS and TEN.PurposeThe
J. Schneider, Philip R. Cohen
semanticscholar   +1 more source

Indirect Comparison of Neoadjuvant Treatment Strategies for Muscle‐Invasive Bladder Cancer: ddMVAC and Perioperative Durvalumab‐Gemcitabine‐Cisplatin Versus Gemcitabine‐Cisplatin: A Systematic Review and Network Meta‐Analysis of Randomised Controlled Trials

International Journal of Cancer, EarlyView.
Optimizing neoadjuvant therapy for muscle‐invasive bladder cancer patients who are eligible for cisplatin remains difficult, owing particularly to high toxicity and recurrence rates. This meta‐analysis compared dose‐dense methotrexate, vinblastine, doxorubicin, and cisplatin (ddMVAC) against durvalumab plus gemcitabine‐cisplatin (D‐GC) and GC alone ...
Maurin Helen Mangold, Gloria Baumann, Victoria Luise Simone Wieland, Nicolas Carl, Luisa Vivienne Renner, Alexander Studier‐Fischer, Hanna Menold, Stefanie Zschäbitz, Frederik Wessels, Niklas Westhoff, Maurice Stephan Michel, Karl‐Friedrich Kowalewski, Caelán Max Haney‐Aubert   +12 more
wiley   +1 more source

Stevens-Johnson Syndrome associated with brucella infection

, 2007
Stevens-Johnson syndrome is a potentially fatal condition that manifests mainly on the skin and mucosal surfaces but also affects other vital organs. There are no report of Stevens-Johnson syndrome caused by brucella infection in the literature.
Kumral, ABDULLAH, Uzuner, NEVİN, Karaman, Ozkan, Caglayan, Sule, Ozer, Erdener, Olmez, Duygu, Asilsoy, SUNA, Babayigit, Arzu   +7 more
core   +1 more source

Current surgical treatment options for ocular complications of Stevens-Johnson and Lyell's syndromes [PDF]

Клиническая офтальмология, 2023
V.F. Chernysh, N.N. Haritonova, A.N. Kulikov, P.A. Kacherovich, A.A. Kol'bin S.M. Kirov Military Medical Academy, St. Petersburg, Russian Federation Epidermolytic drug reactions (EDR) are severe acute drug-induced allergic disorders ...
V.F. Chernysh, N.N. Haritonova, A.N. Kulikov, P.A. Kacherovich, A.A. Kol'bin   +4 more
doaj  

Risk Factors for Cutaneous Immune‐Related Adverse Events in the Japanese Population: A Retrospective Single‐Center Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe, Kohei Yamakawa, Miyu Kobayashi, Yusuke Saigusa, Yukie Yamaguchi   +4 more
wiley   +1 more source

Long-term outcomes of amniotic membrane treatment in acute Stevens-Johnson syndrome/toxic epidermal necrolysis.

The ocular surface, 2020
PURPOSE To report the long-term outcomes of amniotic membrane (AM) use in the form of transplantation (AMT) and self-retained amniotic membrane (ProKera® device, PD) in acute Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN).
S. Shanbhag, Leangelo N. Hall, J. Chodosh, Hajirah N. Saeed   +3 more
semanticscholar   +1 more source

Stevens-Johnson Syndrome After Armodafinil Use

, 2018
: We present the case of a 21-year-old woman in whom Stevens-Johnson syndrome (SJS) developed after initiation of armodafinil. Although this rare and life-threatening reaction is listed on armodafinil's label, no cases have been reported in the ...
Schmidt, Markus, Holfinger, S., Asim Roy, Roy, A., Steven Holfinger, Markus Schmidt   +5 more
core   +1 more source

Clinical validation of the nursing diagnosis of inadequate nutritional intake in children with cancer

International Journal of Nursing Knowledge, EarlyView.
Abstract Purpose To clinically validate the nursing diagnosis “Inadequate Nutritional Intake” based on elements identified within a specific situation theory framework in the context of children with cancer. Methods This is a diagnostic accuracy study following the Standards for Reporting Diagnostic Accuracy Studies (STARD) protocol.
Iane Ximenes Teixeira, Natália Cabrera Matos, Marcos Venícios de Oliveira Lopes, Viviane Martins da Silva, Amanda Laryssa Gomes do Nascimento, Yanka Alcântara Cavalcante, Ana Beatriz Oliveira Marques dos Santos, Daniele Paula Alves Mouta   +7 more
wiley   +1 more source

Efficacy and Tolerability of Weekly Bortezomib, Lenalidomide, and Dexamethasone Protocols in Transplant‐Ineligible Newly Diagnosed Myeloma: An Australian Real‐World, Multicenter Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
RVD with weekly bortezomib dosing in real‐world newly diagnosed transplant‐ineligible myeloma shows comparable efficacy and reduced toxicity compared to twice‐weekly trial protocols. ABSTRACT Background Lenalidomide, bortezomib, and dexamethasone (RVD) remains a standard of care regimen for newly diagnosed multiple myeloma in centers without access to ...
Samantha Kurniawan, Angela Hwang, Nicole Wong Doo, Tracy King, Christian Bryant, Jennifer Zhang, Kristina Whelan, Parisa Fani‐Molky, Giselle Kidson‐Gerber, Annmarie Bosco, Nada Hamad, Gurdeep Parmar, Fiona Kwok, Sam Lai, Silvia Ling, P. Joy Ho, Georgia McCaughan, Adam Bryant   +17 more
wiley   +1 more source