Results 101 to 110 of about 197,989 (298)

Stevens-Johnson syndrome

open access: yesRussian Journal of Skin and Venereal Diseases, 2016
The literature review of the epidemiology, etiology and pathogenesis, clinical presentation and diagnosis of the syndrome of Stevens-Johnson severe life-threatening disease characterized by extensive lesions of the skin and mucous membranes, fever and bone and muscle aches, often induced by medication is presented.
Kseniya V. Ignatieva   +5 more
openaire   +2 more sources

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Incidence of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Nationwide Population-Based Study Using National Health Insurance Database in Korea

open access: yesPLoS ONE, 2016
Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening diseases; however, it is hard to estimate their incidence due to the rarity of these diseases.
Min-Suk Yang   +9 more
semanticscholar   +1 more source

Comprehensive analysis of extracellular matrix remodelling via cyclophilin inhibition in human models of alcohol‐related liver fibrosis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Chronic liver disease and hepatic fibrosis constitute a threat to global health. Clinical translation of preclinical research has been limited, highlighting an urgent need for novel treatments. Cyclophilin inhibitors have shown beneficial effects in liver disease; however, the underlying mechanism of action and the effect across ...
Una Rastovic   +24 more
wiley   +1 more source

Critical insights into the potential risks of antipsychotic drugs to fish, including through effects on behaviour

open access: yesBiological Reviews, EarlyView.
ABSTRACT Antipsychotic drugs (APDs) are a diverse class of neuroactive pharmaceuticals increasingly detected in surface and ground waters globally. Some APDs are classified as posing a high environmental risk, due, in part, to their tendency to bioaccumulate in wildlife, including fish.
Gabrielle Wasser‐Bennett   +4 more
wiley   +1 more source

Diagnosis and management of drug-induced stevens-johnson syndrome: Report of two cases

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2011
Erythema multiforme (EM) is a typically mild, self-limiting and recurring mucocutaneous reaction characterized by target or iris lesions of the skin and mucous membranes.
M Venkateshwarlu, B Radhika
doaj   +1 more source

Erythema Multiforme Versus Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: Subtle Difference in Presentation, Major Difference in Management.

open access: yesMilitary Medicine, 2020
Erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis are immune-mediated epidermal conditions with variable clinical presentations.
R. Newkirk, D. Fomin, M. Braden
semanticscholar   +1 more source

Pollination ecology in the tropical Andes: moving towards a cross‐scale approach

open access: yesBiological Reviews, EarlyView.
ABSTRACT Plant–pollinator interactions structure ecological communities and represent a key component of ecosystem functioning. Pollination networks are expected to be more diverse and specialised in the tropics, but pollination ecology in these regions has been understudied in comparison to other areas.
Cristina Rueda‐Uribe   +25 more
wiley   +1 more source

The Medication Risk of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Asians: The Major Drug Causality and Comparison With the US FDA Label

open access: yesClinical pharmacology and therapy, 2018
Specific ethnic genetic backgrounds are associated with the risk of Stevens–Johnson syndrome / toxic epidermal necrolysis (SJS/TEN) especially in Asians.
Yu-Hsin Wang   +37 more
semanticscholar   +1 more source

Injection Techniques to Reduce Adverse Effects of Subcutaneous Low‐Molecular‐Weight Heparin Among Patients With Cardiovascular Diseases: A Scoping Review

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim(s) To systematically review the existing literature and address the following research question: What are the most effective techniques used to minimise adverse effects resulting from subcutaneous injections of low‐molecular‐weight heparin among patients with cardiovascular diseases? Design A scoping review.
Arkers Kwan Ching Wong   +16 more
wiley   +1 more source

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