Results 21 to 30 of about 128,263 (274)

A Systematic Review of Literature: TNF-α Blockers and JAK Inhibitors for the Treatment of Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, and Severe Forms of Erythema Multiforme. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Stevens‐Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and erythema multiforme major (EM major) are severe dermatologic conditions characterized by varying degrees of skin detachment and involvement of mucosal membranes, often triggered by drug reactions or infections.
Salehi S, Torabi P, Abbaspour M, Hajizadeh N, Sadeghi S, Jafarzadeh A, Goodarzi A.   +6 more
europepmc   +2 more sources

Mycoplasma-pneumonia-induced Stevens–Johnson syndrome in an adult: a case report

Journal of Medical Case Reports
Background Stevens–Johnson syndrome epitomizes an acute, exceptionally rare, and capricious immunological phenomenon marked by potentially life-threatening skin reactions, involvement of mucous membranes, and concomitant systemic manifestations.
Fathima Thesleem Yoosuf, Bassem Al Hariri, Memon Noor Illahi, Muhammad Sharif, Muhammad Yousaf, Mohamed Gaafar Mohamedali, Muayad Kasim Khalid   +6 more
doaj   +2 more sources

Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Review of Diagnosis and Management

Medicina, 2021
Stevens–Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin.
R. Frantz, Simo Huang, Abhi C. Are, K. Motaparthi   +3 more
semanticscholar   +1 more source

Worldwide Prevalence of Antibiotic-Associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review and Meta-analysis.

JAMA dermatology, 2023
Importance Antibiotics are an important risk for Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN), which are the most severe types of drug hypersensitivity reaction with a mortality rate up to 50%.
E. Lee, C. Knox, E. Phillips
semanticscholar   +1 more source

Epidemiology of Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States and factors predictive of outcome

JAAD International, 2023
Background Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS-TEN overlap syndrome are rare severe cutaneous adverse reactions associated with high mortality.
P. Wasuwanich, Joshua M. So, T. Chakrala, Jinghua Chen, K. Motaparthi   +4 more
semanticscholar   +1 more source

Stevens-Johnson syndrome and toxic epidermal necrolysis: A systematic review of PubMed/MEDLINE case reports from 1980 to 2020

Frontiers in Medicine, 2022
Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, life-threatening immunologic reactions. Prior studies using electronic health records, registries or reporting databases are often limited in sample size or lack ...
Liqin Wang, Sheril Varghese, F. Bassir, Ying Lo, Carlos A. Ortega, Sonam N. Shah, K. Blumenthal, E. Phillips, Li Zhou   +8 more
semanticscholar   +1 more source

A Review of the Systemic Treatment of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis

Biomedicines, 2022
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are uncommon but life-threatening diseases mostly caused by drugs. Although various systemic immunomodulating agents have been used, their therapeutic efficacy has been inconsistent ...
Hua-Ching Chang, T. Wang, Ming-Hsiu Lin, Ting-Jui Chen   +3 more
semanticscholar   +1 more source

Bronchiolitis obliterans associated with toxic epidermal necrolysis induced by infection: A case report and literature review

Frontiers in Pediatrics, 2023
BackgroundStevens-Johnson syndrome/toxic epidermal necrolysis has a severe impact on patients' eyes, genital mucosa, and many other organs. Bronchiolitis obliterans is a rare complication of Stevens-Johnson syndrome/toxic epidermal necrolysis.Data ...
Jingwei Liu, Haibo Yan, Chunfeng Yang, Yumei Li   +3 more
doaj   +1 more source

Pembrolizumab-induced Stevens-Johnson syndrome. [PDF]

An Bras Dermatol
de Almeida Junior HL, Sartori DS, Paganelli A, Sias KFB, Capuá LC, Farezin DC.   +5 more
europepmc   +4 more sources

Neutrophils initiate and exacerbate Stevens-Johnson syndrome and toxic epidermal necrolysis

Science Translational Medicine, 2021
Neutrophil extracellular traps induced by drug-specific CD8+ T cells initiate SJS/TEN. Skin-deep drug reactions Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are similar life-threatening forms of severe cutaneous adverse drug ...
M. Kinoshita, Y. Ogawa, N. Hama, I. Ujiie, A. Hasegawa, Saeko Nakajima, T. Nomura, J. Adachi, Takuya Sato, S. Koizumi, S. Shimada, Y. Fujita, Hayato Takahashi, Y. Mizukawa, T. Tomonaga, K. Nagao, R. Abe, T. Kawamura   +17 more
semanticscholar   +1 more source