Multiphysics pharmacokinetic model for targeted nanoparticles
Nanoparticles (NP) are being increasingly explored as vehicles for targeted drug delivery because they can overcome free therapeutic limitations by drug encapsulation, thereby increasing solubility and transport across cell membranes.
Emma M. Glass +7 more
doaj +1 more source
Optimization of one-parameter family of integration formulae for solving stiff chemical-kinetic ODEs
A fast and robust Jacobian-free time-integration method—called Minimum-error Adaptation of a Chemical-Kinetic ODE Solver (MACKS)—for solving stiff ODEs pertaining to chemical-kinetics is proposed herein.
Youhi Morii, Eiji Shima
doaj +1 more source
High order second derivative methods with Runge--Kutta stability for the numerical solution of stiff ODEs [PDF]
We describe the construction of second derivative general linear methods (SGLMs) of orders five and six. We will aim for methods which are A--stable and have Runge--Kutta stability property. Some numerical results are given to show the efficiency of
Ali Abdi, Gholamreza Hojjati
doaj +1 more source
This study introduces a novel one-step hybrid block method for solving both stiff and non-stiff second-order ordinary differential equations (ODEs).
Saidu Daudu Yakubu, Precious Sibanda
doaj +1 more source
Training stiff neural ordinary differential equations with implicit single-step methods. [PDF]
Stiff systems of ordinary differential equations (ODEs) are pervasive in many science and engineering fields, yet standard neural ODE approaches struggle to learn them. This limitation is the main barrier to the widespread adoption of neural ODEs.
Fronk C, Petzold L.
europepmc +3 more sources
Solving Stiff Systems of ODEs by Explicit Methods with Conformed Stability Domains [PDF]
The Cauchy problem for a stiff system of ODEs is considered. The explicit m-stage first order methods of the Runge-Kutta type are designed with stability domains of intermediate numerical schemes conformed with the stability domain of the basic scheme ...
Novikov, A. E. +3 more
core +1 more source
Investigating the Surrogate Modeling Capabilities of Continuous Time Echo State Networks
Continuous Time Echo State Networks (CTESNs) are a promising yet under-explored surrogate modeling technique for dynamical systems, particularly those governed by stiff Ordinary Differential Equations (ODEs).
Saakaar Bhatnagar
doaj +1 more source
High order second derivative multistep collocation methods for ordinary differential equations [PDF]
In this paper, we introduce second derivative multistep collocation meth-ods for the numerical integration of ordinary differential equations (ODEs).
S. Fazeli
doaj +1 more source
Adaptive order of block backward differentiation formulas for stiff ODEs [PDF]
In this paper, Adapative Order of Block Backward Differentiation Formulas (ABBDFs) are formulated using uniform step size for the numerical solution of stiff ordinary differential equations (ODEs). These ABBDF methods are of order four, five and six. The
Zainuddin, Nooraini +3 more
core +1 more source
High order boundary value linear multistep method for the numerical solution of IVPs in ODEs
In this paper, we introduce High order boundary value linear multistep method (HOBVLMM) for the numerical solution of stiff systems of initial value problems (IVPs).
Seun Ogunfeyitimi +2 more
doaj +1 more source

