Results 61 to 70 of about 3,860 (279)
A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair
Advanced Science, EarlyView.A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao +14 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang +10 more
wiley +1 more source
Effect of Forming Process on Compression Characteristics of Composite Hat-stiffened Panels
Cailiao gongcheng, 2018 An experiment was conducted for the composite hat-stiffened panels with different forming process types with boundary constraint, in order to study the effect of secondary bonding and co-curing on the compression stability and carrying capacity of ...
XU Rong-zhang +2 more
doaj +1 more source
Advanced Science, EarlyView.Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu +20 more
wiley +1 more source
Optimization of a Composite Wing Subject to Multi Constraints [PDF]
, 2013 In this thesis, an investigation has been carried out into a minimum weight optimization analysis of a composite wing with multi design constraints under both static and dynamic loadings. The study includes the influence of a morphing leading edge on the
Fu, Qiang
core
Engineering ProceedingsThis study examines how circular and star-shaped damage affects Aluminum-2024-T3 helicopter fuselage panels, focusing on damage shape, size, and location.
Odeh Dababneh, Alex John Pullan
doaj +1 more source
Topology Optimization and Design Guidelines of Sub-Stiffened Panels in Aerospace Applications
MATEC Web of Conferences, 2017 The present work is a proposed optimization model of grid sub-stiffened panels for aerospace applications, having a better knowledge about the stability analysis of conventional grid sub-stiffened panels against loading and different mode of failure ...
Layachi Hemza +2 more
doaj +1 more source
Guideline for Forming Stiffened Panels by Using the Electromagnetic Forces
Metals, 2016 Electromagnetic forming (EMF), as a high-speed forming technology by applying the electromagnetic forces to manufacture sheet or tube metal parts, has many potential advantages, such as contact-free and resistance to buckling and springback.
Jinqiang Tan, Mei Zhan, Shuai Liu
doaj +1 more source
Advanced Science, EarlyView.Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim +2 more
wiley +1 more source
Next MaterialsThe blast or explosion due to terrorist attacks or accidents significantly harms the expensive properties and people. The designing of efficient protective structures at constant mass against these blast loadings is a crucial task.
Murlidhar Patel, Shivdayal Patel
doaj +1 more source