Results 121 to 130 of about 1,332,819 (341)

Corrected method for scaling the dynamic response of stiffened plate subjected to blast load

open access: yesThin-walled structures, 2021
X. Kong   +6 more
semanticscholar   +1 more source

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider   +20 more
wiley   +1 more source

Effects of Partial Edge Loading and Fibre Configuration on Vibration and Buckling Characteristics of Stiffened Composite Plates

open access: yesLatin American Journal of Solids and Structures
In this work, the influence of uniaxial and biaxial partial edge loads on buckling and vibration characteristics of stiffened laminated plates is examined by using finite element method.
T. Rajanna   +3 more
doaj   +1 more source

Composite fuselage technology [PDF]

open access: yes
The overall objective is to identify and understand, via directed experimentation and analysis, the mechanisms which control the structural behavior of fuselages in their response to damage (resistance, tolerance, and arrest).
Graves, Michael J., Lagace, Paul A.
core   +1 more source

Experimental studies on the tripping behavior of narrow T-stiffened flat plates subjected to hydrostatic pressure and underwater shock [PDF]

open access: yes, 1987
An experimental investigation was conducted to determine the static and dynamic responses of a specific stiffened flat plate design. The air-backed rectangular flat plates of 6061-T6 aluminum with an externally machined longitudinal narrow-flanged T ...
Budweg, H. L., Shin, Y. S.
core   +1 more source

An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring

open access: yesAdvanced Science, EarlyView.
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar   +6 more
wiley   +1 more source

Concurrent Topology Optimization of Curved-Plate Structures with Double-Sided Stiffeners

open access: yesMathematics
Due to their high specific stiffness, particularly in bending, along with their strong design capabilities, stiffened plates have become a prevalent structural solution in aerospace and various other fields.
Kai Xu   +3 more
doaj   +1 more source

Catalyst‐Free Collagen Filament Crosslinking for Engineering Anisotropic and Mechanically Robust Tissue Scaffolds

open access: yesAdvanced Science, EarlyView.
A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim   +4 more
wiley   +1 more source

Study of Stability of Unpressurized Shell Structures Under Static Loading, Volume I Final Report [PDF]

open access: yes
Orthotropic shell theory to develop working tools to predict instability in stiffened circular cylindrical shells subjected to axial ...
Dittoe, F. A., Smith, G. W.
core   +1 more source

Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation

open access: yesAdvanced Science, EarlyView.
A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun   +8 more
wiley   +1 more source

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