Results 121 to 130 of about 26,435 (315)

Effective Breadth of Stiffened Plate

Journal of Zosen Kiokai, 1934
As a practical application of the method given in the preceding section, the author investigates the effective breadths in the following cases of plates with parallel sitiffeners, corresponding to the most usual ship structures, such as decks, shells and bulkheads etc., i.e.1.
openaire   +3 more sources

Calculation of skin-stiffener interface stresses in stiffened composite panels [PDF]

A method for computing the skin-stiffener interface stresses in stiffened composite panels is developed. Both geometrically linear and nonlinear analyses are considered.
Cohen, David, Hyer, Michael W.
core   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

Advanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng, Peng Yue, Kaiyu Zhou, Guidong Gong, Yue Zhang, Sha Lin, Xu Liu, Yanjiang Zheng, Siyuan Jing, Junling Guo, Yan Qi, Bi‐Sen Ding, Yimin Hua, Yifei Li   +13 more
wiley   +1 more source

PASCO: Structural panel analysis and sizing code, capability and analytical foundations [PDF]

A computer code denoted PASCO which can be used for analyzing and sizing uniaxially-stiffened composite panels is described. Buckling and vibration analyses are carried out with a linked-plate analysis computer code denoted VIPASA, which is incorporated ...
Anderson, M. S., Stroud, W. J.
core   +1 more source

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

Advanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, Hui Jiang, Qiang Liu, Jingtao Guo, Zhe Zhang, Xiaoyan Wang   +14 more
wiley   +1 more source

Ultrasoft Yet Tough Multifunctional Organohydrogels Enabled by Molecular Chain Lubrication Strategy for Self‐Powered Wearable Electronics

Advanced Science, EarlyView.
An ultrasoft yet tough organohydrogel (AQGL) with 5800% stretchability and 14.3 kPa modulus is developed via a novel molecular chain lubrication strategy. It features optical transparency, drying/freezing (−40°C) tolerance, antibacterial activity, conductivity, self‐healing, and adhesiveness.
Si Wang, Lin Hu, Mingbo Pu, Mingfeng Xu, Tao Zhou, Hanbing Rao, Xiong Li, Xiaoliang Ma, Gehong Su, Xiangang Luo   +9 more
wiley   +1 more source

Transport composite fuselage technology: Impact dynamics and acoustic transmission [PDF]

A program was performed to develop and demonstrate the impact dynamics and acoustic transmission technology for a composite fuselage which meets the design requirements of a 1990 large transport aircraft without substantial weight and cost penalties. The
Balena, F. J., Jackson, A. C., Labarge, W. L., Pei, G., Pitman, W. A., Wittlin, G.   +5 more
core   +1 more source

Understanding Glioblastoma Dynamics Using 3D Organoids and Engineered Extracellular Matrix

Advanced Science, EarlyView.
A modular in vitro glioblastoma multiforme (GBM) model combining patient‐derived glioma stem‐like cells (GSC) organoid with an engineered extracellular matrix (eECM) and endothelial co‐culture enhances differentiation and GBM associated gene expression.
Autumn McManis, Charles Ashley Jimenez, Abha Shirolkar, Syed Raza ur Rehman, Sumana Mallick, Malea Murphy, Akhilesh K. Gaharwar, Irtisha Singh   +7 more
wiley   +1 more source

Composite fuselage technology [PDF]

The overall objective is to identify and understand, via directed experimentation and analysis, the mechanisms which control the structural behavior of fuselages in their response to damage (resistance, tolerance, and arrest).
Graves, Michael J., Lagace, Paul A.
core   +1 more source