Results 131 to 140 of about 26,435 (315)
Advanced Science, EarlyView.This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang +10 more
wiley +1 more source
Sustainable StructuresThis paper presents two types of metal dampers for beam-column joints based on the replaceability design concept after an earthquake. A low-cyclic loading test of slit/corrugated dampers was conducted, revealing the failure and load-bearing mechanisms ...
Hongchao Guo +5 more
doaj +1 more source
Minimum weight design of symmetrically stiffened orthotropic cylinders under axial compression [PDF]
Minimum weight design of symmetrically stiffened orthotropic cylinders under axial ...
Gerard, G., Lakshmikantham, C.
core +1 more source
Highly Aligned Bacteria Cellulose Yarn Aggregation for Energy Generation and Strain Sensing
Advanced Science, EarlyView.Although high‐performance bacterial cellulose fibers have attracted significant interest for wearable electronics, a self‐powered and high‐mechanosensitive design is still scarce for achieving an intelligent integrated system. Here, we demonstrate an innovative bio‐fabrication strategy to develop a core‐sheath yarn that features the ordered network and
Chong Gao +9 more
wiley +1 more source
Analytical and experimental study of structurally efficient composite hat-stiffened panels loaded in axial compression [PDF]
Structural efficiency studies were made to determine the weight saving potential of graphite/epoxy composite structures for compression panel applications.
Mikulus, M. M., Jr., Williams, J. G.
core +1 more source
Advanced Science, EarlyView.Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong +21 more
wiley +1 more source
Computer program for buckling loads of orthotropic laminated stiffened panels subjected to biaxial in-place loads (BUCLASP 2) [PDF]
, 1974 General-purpose program performs exact instability analyses for structures such as unidirectionally-stiffened, rectangular composite panels.
Tamekuni, M., Viswanathan, A. V.
core +1 more source
Advanced Science, EarlyView.It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan +13 more
wiley +1 more source
Study of Stability of Unpressurized Shell Structures Under Static Loading, Volume I Final Report [PDF]
Orthotropic shell theory to develop working tools to predict instability in stiffened circular cylindrical shells subjected to axial ...
Dittoe, F. A., Smith, G. W.
core +1 more source
Advanced Science, EarlyView.Compared to a healthy random nanofibrous fibronectin microenvironment, a fibrotic aligned nanofibrous fibronectin microenvironment employs a specific integrin, α5β1 integrin, to activate early pro‐fibrotic fibroblast behaviors and later fibrotic fibroblast tissue formation with cell/F‐actin alignment, α‐SMA expression, and cell‐driven aligned ...
Doğuhan Beyatlı +3 more
wiley +1 more source