Results 141 to 150 of about 1,332,819 (341)

An investigation of the parametric resonance of rectangular plates reinforced with closely spaced stiffeners [PDF]

Parametric resonance and structural stability model of uniformly reinforced flat ...
Duffield, R. C., Willems, N.
core   +1 more source

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source

Calculation of skin-stiffener interface stresses in stiffened composite panels [PDF]

A method for computing the skin-stiffener interface stresses in stiffened composite panels is developed. Both geometrically linear and nonlinear analyses are considered.
Cohen, David, Hyer, Michael W.
core   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Computer program for buckling loads of orthotropic laminated stiffened panels subjected to biaxial in-place loads (BUCLASP 2) [PDF]

, 1974
General-purpose program performs exact instability analyses for structures such as unidirectionally-stiffened, rectangular composite panels.
Tamekuni, M., Viswanathan, A. V.
core   +1 more source

Ambient Stable Triboelectric Nanogenerator Based on Conductive Filler Modified Silicone Rubber with Gas Barrier Encapsulation for Footstep Energy Conversion

Advanced Science, EarlyView.
A humidity‐tolerant triboelectric nanogenerator is developed using conductive carbon black‐modified silicone rubber and a flame‐retardant gas barrier layer. The device efficiently harvests footstep energy while maintaining stable output under 30–90% RH and over 1 million cycles.
Yi Wei, Yushu Tian, Xiaokang Chen, Junfeng Chu, Junjie Wang, Xiangyu Chen, Wenjie Wu, Liqun Zhang   +7 more
wiley   +1 more source

Vibrations and structureborne noise in space station [PDF]

Analytical models were developed to predict vibrations and structureborne noise generation of cylindrical and rectangular acoustic enclosures. These models are then used to determine structural vibration levels and interior noise to random point input ...
Bofilios, D. A., Lyrintzis, C. S., Vaicaitis, R.   +2 more
core   +1 more source

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

Advanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng, Peng Yue, Kaiyu Zhou, Guidong Gong, Yue Zhang, Sha Lin, Xu Liu, Yanjiang Zheng, Siyuan Jing, Junling Guo, Yan Qi, Bi‐Sen Ding, Yimin Hua, Yifei Li   +13 more
wiley   +1 more source

Experimental and theoretical study of replaceable energy-dissipation devices for beam-column joints under cyclic loads

Sustainable Structures
This paper presents two types of metal dampers for beam-column joints based on the replaceability design concept after an earthquake. A low-cyclic loading test of slit/corrugated dampers was conducted, revealing the failure and load-bearing mechanisms ...
Hongchao Guo, Yuwei Li, Dongdong Zheng, Wenqi Wang, Renzhang Song, Yunhe Liu   +5 more
doaj   +1 more source

Composite fuselage technology (summary of year 2) [PDF]

The overall objective of this work is to identify and understand, via directed experimentation and analysis, the mechanisms which control the structural behavior of fuselages in their response to damage (resistance, tolerance, and arrest).
Graves, Michael J., Lagace, Paul A.
core   +1 more source