Results 151 to 160 of about 1,332,819 (341)

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

open access: yesAdvanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang   +14 more
wiley   +1 more source

Composite transport wing technology development: Design development tests and advanced structural concepts [PDF]

open access: yes
Numerous design concepts, materials, and manufacturing methods were investigated for the covers and spars of a transport box wing. Cover panels and spar segments were fabricated and tested to verify the structural integrity of design concepts and ...
Griffin, Charles F., Harvill, William E.
core   +1 more source

3D‐Printed Ion‐Conductive Hydrogels with Tunable Mechanical–Electrical Properties for Multimodal Sign Language Recognition

open access: yesAdvanced Science, EarlyView.
This work successfully fabricated ion‐conductive hydrogels with low hysteresis and high conductivity using 3D printing technology. By adjusting the component ratios, the properties of the hydrogels can be tuned to meet diverse sensing requirements. Finally, a multimodal sensing sign language recognition system was constructed based on this hydrogel ...
Quan Hu   +9 more
wiley   +1 more source

A metal sheet stiffened by a partially debonded composite quarter-plate [PDF]

open access: yes
An isotropic sheet stiffened by means of an orthotropic quarter-plate is considered. The quarter-plate is assumed to be perfectly bonded to the metal sheet everywhere except an area of debonding which may develop due to high stress concentrations.
Arin, K.
core   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

open access: yesAdvanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu   +10 more
wiley   +1 more source

Design of anisotropic plates for improved damage tolerance [PDF]

open access: yes
An analytical study is presented showing the effects of the notch tip geometry on the location and direction of crack growth from an existing notch in a unidirectional fibrous composite modeled as a homogeneous, anisotropic, elastic material. Anisotropic
Guerdal, Zafer
core   +1 more source

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

open access: yesAdvanced Science, EarlyView.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside   +11 more
wiley   +1 more source

Application of genetic algorithms to the evaluation of the fundamental frequency of stiffened plates

open access: yesArchives of Acoustics, 2014
In this paper, the analytical and numerical procedures for multi-stiffened plate free vibration analysis are presented. The plate and stiffeners are treated as an assembled plate and stiffening elements.
M. IWANIEC
doaj  

Ultrasoft Yet Tough Multifunctional Organohydrogels Enabled by Molecular Chain Lubrication Strategy for Self‐Powered Wearable Electronics

open access: yesAdvanced Science, EarlyView.
An ultrasoft yet tough organohydrogel (AQGL) with 5800% stretchability and 14.3 kPa modulus is developed via a novel molecular chain lubrication strategy. It features optical transparency, drying/freezing (−40°C) tolerance, antibacterial activity, conductivity, self‐healing, and adhesiveness.
Si Wang   +9 more
wiley   +1 more source

Minimum weight design of symmetrically stiffened orthotropic cylinders under axial compression [PDF]

open access: yes
Minimum weight design of symmetrically stiffened orthotropic cylinders under axial ...
Gerard, G., Lakshmikantham, C.
core   +1 more source

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