Results 101 to 110 of about 21,851 (314)

Structural optimization by generalized, multilevel decomposition [PDF]

open access: yes
The developments toward a general multilevel optimization capability and results for a three-level structural optimization are described. The method partitions a structure into a number of substructuring levels where each substructure corresponds to a ...
James, B. B.   +2 more
core   +1 more source

3D‐Printing Aided Rapid Prototyping of Pretensioned Tensegrity Structures for Robotic Applications

open access: yesAdvanced Robotics Research, EarlyView.
Printing, injection molding, and assembly (PMA) is a method for rapid prototyping mesoscale, topologically complex, and tensioned tensegrity structures. In combination with PMA method, two mold design strategies: modular mold and compact channel layout, enable efficiency and scalability for tensegrity fabrication.
Yi Sun   +3 more
wiley   +1 more source

Postbuckling delamination of a stiffened composite panel using finite element methods [PDF]

open access: yes
A combined numerical and experimental study is carried out for the postbuckling behavior of a stiffened composite panel. The panel is rectangular and is subjected to static in-plane compression on two opposite edges to the collapse level.
Babcock, C. D.   +2 more
core   +1 more source

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee   +9 more
wiley   +1 more source

An investigation of the parametric resonance of rectangular plates reinforced with closely spaced stiffeners [PDF]

open access: yes
Parametric resonance and structural stability model of uniformly reinforced flat ...
Duffield, R. C., Willems, N.
core   +1 more source

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider   +20 more
wiley   +1 more source

Composite reinforced propellant tanks [PDF]

open access: yes
Design studies involving weight and cost were carried out for several structural concepts applicable to space shuttle disposable tankage. An effective design, a honeycomb stabilized pressure vessel, was chosen.
Aleck, B. J.   +3 more
core   +1 more source

Analysis of Clamped Square Plates Containing Openings with Stiffened Edges [PDF]

open access: yes, 1961
National Science Foundation Grant No.
Ang, A.H-S., Prescott, W.S., Siess, C.P.
core  

In Situ Characterisation of Hydrogels via Dynamic Interface Printing

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels have become pivotal materials for tissue engineering, robotics, biomedical devices, and sensing applications due to their diverse material compositions and tunable mechanical properties. While significant effort has focused on developing novel manufacturing approaches such as extrusion bioprinting and light‐based fabrication methods,
Callum Vidler   +2 more
wiley   +1 more source

Constructal Design and Numerical Simulation Applied to Geometric Evaluation of Stiffened Steel Plates Subjected to Elasto-Plastic Buckling Under Biaxial Compressive Loading

open access: yesMetals
Widely employed in diverse engineering applications, stiffened steel plates are often subjected to biaxial compressive loads. Under these conditions, buckling may occur, initially within the elastic range but potentially progressing into the elasto ...
Andrei Ferreira Lançanova   +7 more
doaj   +1 more source

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