Results 141 to 150 of about 21,851 (314)

Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions

Advanced Science, EarlyView.
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan, Keshav Gajendra Babu, Markus Mukenhirn, Antje Garside, Vinita Ajit Kini, Trishla Adhikari, Timon Beck, Byung Ho Lee, Kyoohyun Kim, Carsten Werner, Raimund Schlüßler, Alf Honigmann, Sebastian Aland, Anna Verena Taubenberger   +13 more
wiley   +1 more source

Aligned Fibronectin Microenvironment Temporally Facilitates Profibrotic Fibroblast Activation via Integrin α5β1

Advanced Science, EarlyView.
Compared to a healthy random nanofibrous fibronectin microenvironment, a fibrotic aligned nanofibrous fibronectin microenvironment employs a specific integrin, α5β1 integrin, to activate early pro‐fibrotic fibroblast behaviors and later fibrotic fibroblast tissue formation with cell/F‐actin alignment, α‐SMA expression, and cell‐driven aligned ...
Doğuhan Beyatlı, Mika Brown, George‐Radu Romanescu, Seungkuk Ahn   +3 more
wiley   +1 more source

Effect of stress concentrations in composite structures [PDF]

The goal of achieving a better understanding of the failure of complex composite structure is sought. This type of structure requires a thorough understanding of the behavior under load both on a macro and micro scale if failure mechanisms are to be ...
Babcock, G. D., Knauss, W. G.
core   +1 more source

Dynamic Supramolecular Polyurethane Elastomers Enabling Bioinspired Strain‐Adaptive Stiffening to Resolve the Softness–Strength Paradox

Advanced Science, EarlyView.
Segmental‐level molecular engineering of a supramolecular polyurethane elastomer integrates strain‐adaptive chains, soft elastic segments, and dynamic hydrogen bonding motifs. This design reconciles skin‐like softness with muscle‐level strength, offering a sustainable and high‐performance material platform for next‐generation artificial skin and soft ...
Haoming Zou, Zhi‐Xiong Fei, Zhao Yang, Ke‐Ke Yang, Dong‐Xu Yang, Ling‐Ying Shi   +5 more
wiley   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source

Experimental and theoretical study of replaceable energy-dissipation devices for beam-column joints under cyclic loads

Sustainable Structures
This paper presents two types of metal dampers for beam-column joints based on the replaceability design concept after an earthquake. A low-cyclic loading test of slit/corrugated dampers was conducted, revealing the failure and load-bearing mechanisms ...
Hongchao Guo, Yuwei Li, Dongdong Zheng, Wenqi Wang, Renzhang Song, Yunhe Liu   +5 more
doaj   +1 more source

Improvements to a method for the geometrically nonlinear analysis of compressively loaded stiffened composite panels [PDF]

This report describes progress made during the period July 1991 to December 1991 on the tasks identified in the technical proposals for the subject grant. The plans for further effort on each of the tasks are outlined.

core   +1 more source

Data‐Driven Design of Bimodal Networked Dielectric Elastomers for High‐Performance Artificial Muscles

Advanced Intelligent Systems, EarlyView.
A data‐efficient artificial intelligence‐assisted framework, which integrates experimental data with machine learning, is developed for the design of bimodal networked dielectric elastomers (DEs) as advanced artificial muscles. It adopts neural networks to predict DEs’ mechanical properties and support vector machines to classify electromechanical ...
Ofoq Normahmedov, Hanzhi Ma, Junbo Peng, Huifeng Dong, Jiangshan Zhuo, Mengke Shi, Lvting Wang, Shengchao Jiang, Ye Shi   +8 more
wiley   +1 more source

Development of lightweight aluminum compression panels reinforced by boron-epoxy infiltrated extrusions [PDF]

Analytical and experimental studies were performed to evaluate the structural efficiencies afforded by the selective reinforcement of conventional aluminum compression panels with unidirectional boron epoxy composite materials.
Henshaw, J., Mcelman, J. A., Roy, P. A.
core   +1 more source

Scalable High‐Force Zipping Electrostatic Actuators

Advanced Intelligent Systems, EarlyView.
An electrostatic actuator architecture is presented that combines high energy density with forces and strokes suited for wearable soft robotics. By folding patterned thin films into a scalable honeycomb of zipping units, performance becomes tunable through series–parallel design, achieving over 40 N and 28 J/kg.
Fabio Caruso, Amir Firouzeh, Herbert Shea   +2 more
wiley   +1 more source