Results 171 to 180 of about 1,096 (259)

Small Extracellular Vesicle‐Derived Nidogen 1 Promotes HCC Carcinogenesis via Transglutaminase 3‐Mediated YAP/TAZ Signalling

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
NID1‐rich sEVs released by HCC cells are internalized by recipient cells, where the C‐terminal region of NID1 binds to and stabilizes TGM3. This activates integrin‐FAK/Src/AKT and Hippo‐YAP/TAZ signalling, thereby promoting HCC proliferation, colony formation, migration, invasion, tumour growth, and lung metastasis.
Cherlie Lot Sum Yeung   +9 more
wiley   +1 more source

Abstracts

open access: yesMolecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Integrated Design and Process Optimization of FDM‐Fabricated Hexagonal Architected Thin‐Walled PA12 Tubes for Improved Compressive and Energy Absorption Performance

open access: yesMacromolecular Materials and Engineering, Volume 311, Issue 8, August 2026.
FDM‐fabricated PA12 thin‐walled tubes with five hexagonal architected designs (D1–D5) of increasing nodal connectivity were investigated to determine the effects of wall architecture, layer height, and print angle orientation on compressive performance, energy absorption, and dimensional accuracy.
Vigneshwaran Karupaiah   +4 more
wiley   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang   +9 more
wiley   +1 more source

Effect of Foam Faces and Butterfly Auxetic Core on Sandwich Nanoplate Vibration and Buckling

open access: yesZAMM - Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik, Volume 106, Issue 8, August 2026.
ABSTRACT This research examines the thermomechanical vibration and buckling properties of a three‐layer sandwich nanoplate, which consists of foam face layers and a butterfly‐shaped auxetic core. The formulation is developed based on Hamilton's principle and higher‐order shear deformation theory (HSDT), utilizing an analytical Navier‐type solution to ...
Mustafa Eroğlu   +2 more
wiley   +1 more source

3D Wave Dispersion Analysis of Sandwich Plates With GPRL‐Reinforced FGM Face Layers Containing Anti‐Tetrachiral Auxetic Metamaterials

open access: yesZAMM - Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik, Volume 106, Issue 8, August 2026.
ABSTRACT In this study, the 3D wave dispersion properties of a metamaterial nanoplate with GPRL‐reinforced functionally graded material (FGM) surface layers were investigated using refined sinusoidal shear deformable plate theory (RSSDT) and nonlocal strain gradient theory (NSGT).
Engin Yıldırım
wiley   +1 more source

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