Results 131 to 140 of about 105,641 (310)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Relationship Between Increased In Vivo Meniscal Loads and Abnormal Tibiofemoral Surface Alignment in ACL deficient Sheep is Varied [PDF]

open access: yes, 2016
Adeeb   +45 more
core   +2 more sources

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Machines as Engines of Growth [PDF]

open access: yes
This paper builds a model of growth through industrialization, where machines replace workers in a growing number of tasks. This enables the economy to experience long-run growth, as machines become servants of humans, and as their number grows ...
Joseph Zeira
core  

A Maximal Panning Tree [PDF]

open access: yes, 1994
The five-letter word network given below is partitioned into 27 subnetworks, each having a unique vowel-consonant pattern (Y in first position is deemed a consonant, otherwise a vowel).
Eckler, A. Ross
core   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari   +3 more
wiley   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang   +10 more
wiley   +1 more source

Patellar luxation in dogs

open access: yesVeterinary Medicine: Research and Reports, 2018
Francesco Di Dona, Giovanni Della Valle, Gerardo Fatone Department of Veterinary Medicine and Animal Productions, University of Napoli “Federico II”, Naples, Italy Abstract: Patellar luxation is a common orthopedic problem in dogs.
Di Dona F, Della Valle G, Fatone G
doaj  

Tenure Insecurity, Adverse Selection, and Liquidity in Rural Land Markets [PDF]

open access: yes
A theory of land market activity is developed for settings where there is uncertainty and private information about the security of land tenure. Land sellers match with buyers in a competitive search environment, and an illiquid land market emerges as a ...
Derek Stacey
core  

Home - About - Disclaimer - Privacy