Results 201 to 210 of about 124,061 (401)

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

open access: yesAdvanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams   +7 more
wiley   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Case Study: Australia's Computer Games Audience and Restrictive Ratings System [PDF]

open access: yes
Computer and video games are big business in Australia, just as they are in many other developed economies. However, Australia is unique among developed states because there is no R18+ or "Adult" rating for computer game content in Australia. The present
Jeffrey E. BRAND   +2 more
core  

Engineering the Link: From Genome Interaction Maps to Functional Insight

open access: yesAdvanced Biology, EarlyView.
Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen   +5 more
wiley   +1 more source

Numerical Model and Experimental Validation of Composite Metal Foam in Protecting Carbon Steel Against Puncture

open access: yesAdvanced Engineering Materials, EarlyView.
The puncture prevention and energy absorption performance of composite metal foam (CMF) are studied experimentally and numerically for hazardous materials transportation protection. The numerical model implementing air within the CMF (nonhomogeneous model using fluid cavity technique) predicts puncture more accurately compared to the homogeneous CMF ...
Aman Kaushik, Afsaneh Rabiei
wiley   +1 more source

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