Results 211 to 220 of about 4,403 (296)

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

Long-Term Health Consequences of SARS-CoV-2- Trigger for Still Disease in Adults. [PDF]

ACR Open Rheumatol
Zavidić T, Dejhalla E, Lesac Brizić A, Popović B.   +3 more
europepmc   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Unfolding dermatological spectrum of Still's disease: a cohort study from the International AIDA Network Still's Disease Registry. [PDF]

Rheumatology (Oxford)
Calabrese L, D'Onghia M, Cartocci A, Hinojosa-Azaola A, Torres-Ruiz J, Lopalco G, Sbalchiero J, Caggiano V, Giardini HAM, Almaghlouth IA, Ruscitti P, Di Cola I, Sfikakis PP, Laskari K, Sfriso P, Dagna L, Campochiaro C, Tufan A, Kucuk H, Kardas RC, Erden A, Ragab G, Hegazy MT, Laymouna AH, Navarini L, Berardicurti O, Ciccia F, Iacono D, Riccio F, Fotis L, Direskeneli H, Makowska J, Iagnocco A, Conforti A, Rigante D, Thabet M, Iannone F, Domanico D, Govoni M, Maggio MC, Del Giudice E, La Torre F, Batu ED, Ozen S, Gaggiano C, Martín-Nares E, Guaracha-Basañez GA, Karamanakos A, Lo Gullo A, Monosi B, Bartoloni E, Hernández-Rodríguez J, Gómez-Caverzaschi V, Emmi G, Erten S, Carubbi F, Gicchino MF, De Paulis A, Conti G, Ogunjimi B, Wiesik-Szewczyk E, Nowakowska-Płaza A, Viapiana O, Sarzi-Puttini P, Tharwat S, Crisafulli F, Parronchi P, Gidaro A, De Stefano L, Breda L, La Barbera L, Guggino G, Balistreri A, Fabiani C, Rubegni P, Frediani B, Giacomelli R, Cantarini L, Vitale A, International AIDA (AutoInflammatory Diseases Alliance) Network and the Autoinflammatory Diseases Working Group of the Italian Society of Rheumatology (SIR).   +79 more
europepmc   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Challenges on diagnosis and treatment of refractory adult-onset still disease in Sub-Saharan Africa: a case report. [PDF]

J Med Case Rep
Simeni Njonnou SR, Kemta Lekpa F, Essoka Essoka AR, Ntsama Essomba MJ, Moulion Tapouh JR, Nguemo C, Soh Maleu F, Noubom M.   +7 more
europepmc   +1 more source

Climate und Rheumatic Diseases [PDF]

, 1992
Baenkler, Hanns-Wolf, Schuh, Angela, Senn, E.   +2 more
core  

Adult-onset Still disease [PDF]

, 2020
openaire   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

Pregnancy-Associated Onset of Adult-Onset Still's Disease

American Journal of Perinatology Reports
Nawras Zayat, Avish Arora, Joselle O'Brien, Japjot Bal, Rebekah Sugarman, Leeshun Rivera, Amir Shamshirsaz, Kavita Vani, Dimitrios S. Mastrogiannis   +8 more
doaj   +1 more source