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Treatment of adult-onset Still's disease: a review [PDF]
Adult-onset Still's disease (AOSD) is a rare inflammatory disorder that has been recently classified as a polygenic autoinflammatory disorder. The former classification, based on the disease course, seems to be quite dated.
Gerfaud-Valentin, M. +3 more
core +3 more sources
First described in 1971, adult-onset Still's disease (AOSD) is a rare multisystemic disorder considered as a complex (multigenic) autoinflammatory syndrome. A genetic background would confer susceptibility to the development of autoinflammatory reactions to environmental triggers.
Gerfaud-Valentin, Mathieu +3 more
openaire +5 more sources
Adult-onset Still’s disease is a rare inflammatory disorder characterised by fever, arthritis and rash. It can present in a number of ways and is associated in 5% of cases with parenchymal lung involvement.
Robert Perry +4 more
doaj +1 more source
Elevated Troponin Serum Levels in Adult Onset Still's Disease [PDF]
Adult onset Still's disease (AOSD) is a rare inflammatory systemic disease that occasionally may affect myocardium. Diagnosis is based on typical AOSD symptoms after the exclusion of well-known infectious, neoplastic, or autoimmune/autoinflammatory ...
Brugioni, Lucio +7 more
core +3 more sources
Development and Role in Therapy of Canakinumab in Adult-Onset Still's Disease [PDF]
Adult-onset Still's disease (AOSD) is a rare inflammatory disease of unknown etiology typically characterized by episodes of spiking fever, evanescent rash, arthralgia, leukocytosis, and hyperferritinemia. The pivotal role of interleukin (IL)-1 and other
Baggio, Chiara +4 more
core +1 more source
Adult-onset Still's Disease: A Case Report
Adult-onset Still’s Disease is a rare auto inflammatory disorder of unknown etiology characterized mainly by high spiking fever, arthritis, evanescent rash and lymphadenopathy.
Ashok Sapkota +4 more
doaj +1 more source
Adult‐onset Still's disease complicated by macrophage activation syndrome
Key Clinical Message Young patients with persistent rash and fevers despite antibiotic treatment should be evaluated for non‐infectious etiologies. In our patient's case, these findings led to a diagnosis of MAS, which ultimately affected how she was ...
Toluwalase Awoyemi +2 more
doaj +1 more source
Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis [PDF]
Introduction There has been no report in the literature of a soluble form of interleukin (IL)-18 receptor α (IL-18Rα). In this study, we evaluated the levels and characteristics of soluble IL-18Rα (sIL-18Rα) in the sera of patients with ...
Satoko Takei +12 more
core +1 more source
BACKGROUND:. We report a case of a young woman with adult-onset Still’s disease presenting as macrophage-activation syndrome complicated by shock and respiratory failure during the third trimester of pregnancy. CASE SUMMARY:. A previously healthy 26-year-
Andrew T. Peters, MD +1 more
doaj +1 more source
A 24-year-old male presented with fever, sore throat, and arthralgias for duration of 4 weeks. Fever was high grade, intermittent, associated with maculopapular rash. He was admitted in outside hospital and was started on antibiotics, antituberculosis treatment (ATT), and anti-malarials. The patient was discharged without any improvement.
Srinivas +2 more
openaire +4 more sources

