Results 201 to 210 of about 61,138 (307)

Evaluating the Utility of RNAseq in Prenatal Diagnostics: Expression Profiles of Cultured Chorionic Villus and Amniotic Fluid Samples

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective While RNAseq has enhanced variant interpretation in postnatal cases, its potential in the prenatal setting remains underexplored. This study investigates the utility of RNAseq in prenatal diagnostics by analyzing the expression profiles of cultured chorionic villus samples (cCVS) and amniotic fluid (cAF) samples. Methods We performed
Maria C. Vladoiu, Sen Zhao, Roni Zemet, Christian M. Parobek, Jefferson Cruz Sinson, Stacy Tankersley, Ignatia B. Van den Veyver, Pengfei Liu   +7 more
wiley   +1 more source

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source

Study protocol to develop bereavement care package for the Indian healthcare system to support parents of stillborn babies. [PDF]

BMC Pregnancy Childbirth
Mukherjee R.
europepmc   +1 more source

Is There Potential Clinical Utility in Reporting Variants of Uncertain Significance From Prenatal Sequencing?

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal sequencing of fetuses with abnormalities detected on imaging is expanding globally. Debate continues over whether variants of uncertain significance (VUS) should be reported prenatally, with some recent national position statements opposing this.
A. Gibbs, R. Braham, V. Ramachandran, R. Roberts, C. Willison, T. Ashraf, J. Cobben, A. Gardham, M. Holder‐Espinasse, T. Homfray, S. G. Mehta, D. Tapon, P. Vasudevan, N. J. Chandler   +13 more
wiley   +1 more source

Evaluating and Refining Claims-Based Algorithms for Pregnancy Outcomes and Gestational Age Estimation in Korea. [PDF]

J Korean Med Sci
Kim HJ, Cho H, Jung SY, Shin JY, Choe SA, Choi NK.   +5 more
europepmc   +1 more source

Placental Dysfunction and Congenital Heart Disease: Investigating the Placenta‐Heart Axis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Concurrent development of the placenta and heart during early gestation suggests a shared biological basis for the co‐occurrence of abnormal placentation and congenital heart disease (CHD). This study investigated the association between placental vascular pathology and CHD type.
Natalie Lanners, Sarah U. Morton, Katherine Le, Steffy Blanco, Sara Mansoorshahi, Chrystalle Katte Carreon, Christina Ronai, Louise Wilkins‐Haug, Vidhya Annavajjhala, Jacqueline G. Parchem, Tina O. Findley   +10 more
wiley   +1 more source

"If there is no data, how do we improve?" Exploring health workers' perspective on stillbirth recording in the Ashanti Region of Ghana. [PDF]

BMC Pregnancy Childbirth
Mensah Abrampah NA, Okwaraji YB, Oteng KF, Asiedu EK, Larsen-Reindorf R, Blencowe H, Jackson D, Jackson D.   +7 more
europepmc   +1 more source

Exploring the Reproductive Toxicity of Bisphenol S Through a Network Toxicology and Molecular Docking Analysis

Pediatric Discovery, EarlyView.
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang, Yan Fu, Xu Huang, Qitong Guo, Xiangqin Zheng, Shengde Wu, Lianju Shen, Guanghui Wei   +7 more
wiley   +1 more source

Clinical Utility of Stillbirth Investigations in Australia: A Cohort Study. [PDF]

Aust N Z J Obstet Gynaecol
Marsden T, Cheng M, Khong TY, Dahlstrom JE, Ellwood D, Moghimi A, Prystupa S, Obrien C, Cassim FS, Martin S, Coory M, Boyle FM, Shukralla H, Kent AL, Varikara AK, Hannaford P, Frost J, Perry-Keene J, Pomare G, Wong YP, Tan GC, Flenady V, Sexton J.   +22 more
europepmc   +1 more source

Maternal Circulating sFlt-1:PlGF Ratio and Stillbirth.

JAMA Netw Open
Lee MS, Eum KD, Christiani DC.
europepmc   +1 more source