Results 41 to 50 of about 55,587 (276)

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Variant filtering in WGS data of a stillborn puppy with hydranencephaly.

, 2023
Variant filtering in WGS data of a stillborn puppy with hydranencephaly.
José Suárez Sánchez-Andrade (16426153), Iris M. Reichler (16426150), Claude Schelling (50030), Orsolya Balogh (3425144), Aldona Pieńkowska-Schelling (4179472), Matthias Christen (1363884), Marilisa Novacco (3573917), Bianca Lourdes Frehner (16426147), Anja Kipar (87443), Vidhya Jagannathan (13914), Barbara Riond (3418865), Tosso Leeb (81674), Laureen M. Peters (8543934)   +12 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Is It Possible to Prevent the Thanatogenetic Processes in Premature Babies?

Clinics and Practice
Preterm births comprise all pregnancies coming to an end before the gestational age of 37 weeks and remain the leading cause of death in children under 5 years old despite efforts to reduce their occurrence.
Sinziana Andra Ghitoi, Mariana Deacu, Mariana Aschie, Manuela Enciu, Anca Florentina Mitroi, Georgeta Camelia Cozaru, Antonela Anca Nicolau, Cristian Ionut Orasanu, Oana Andreea Ursica, Raluca Ioana Voda   +9 more
doaj   +1 more source

Number of stillborn infants, stillborn rates, and relative risk of stillbirth, out of the male and female SGA cohorts as classified by unadjusted and sex-specific charts, at preterm and term gestations.

, 2022
Number of stillborn infants, stillborn rates, and relative risk of stillbirth, out of the male and female SGA cohorts as classified by unadjusted and sex-specific charts, at preterm and term gestations.
Susan P. Walker (7464881), Natasha L. Pritchard (7464863), Stephen Tong (310909), Alexandra R. Mitchell (13933116), Anthea C. Lindquist (7464884)   +4 more
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

FEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

Arthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok, Samantha Morais, William K. Silverstein, Clare L. Atzema, Gregory Choy, Priyanka Chandratre, Ping Li, Jessica Widdifield   +7 more
wiley   +1 more source

The Association of Gout Flare Resolution With Physical Activity and Sleep: A Prospective Remote‐Monitoring Study

Arthritis Care &Research, EarlyView.
Objective This study aimed to determine whether gout flare resolution is associated with physical activity and sleep. These findings were intended to inform the future development of a definition for flare resolution. Methods Data from 81 participants with gout who experienced at least one flare during a six‐month prospective observational study were ...
Sarah Stewart, Boston Girven, Mia Clarke, Irene Zeng, Angelo Gaffo, Lisa K. Stamp, N. Lawrence Edwards, David Rice, Tania Ka'ai, Karl Rudolph, Julie Collis, Nicola Kayes, Nicola Dalbeth   +12 more
wiley   +1 more source

Physics‐Grounded Materials Artificial Intelligence for Reliable Materials Discovery

Advanced Functional Materials, EarlyView.
Physics‐Grounded Materials AI (PhysMat AI) integrates physical priors, descriptors, constraints, verification, and data infrastructure into a unified full‐stack framework, enabling reliable, interpretable, and autonomous AI‐driven materials discovery.
Yuhang Wang, Qian Wang, Seong‐Hoon Jang, Hao Li   +3 more
wiley   +1 more source