Mutation in sorghum LOW GERMINATION STIMULANT 1 alters strigolactones and causes Striga resistance
Proceedings of the National Academy of Sciences of the United States of America, 2017 D. Gobena +7 more
semanticscholar +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Rural communities’ perception on Monsonia angustifolia E. Mey. ex. A. Rich.: its value, benefits and uses in South Africa [PDF]
Journal of Medicinal PlantsBackground: South Africa is endowed with an abundance of diverse medicinal plant species and in the Limpopo Province, Bapedi people continue to use Monsonia angustifolia as a tea and herb to cure ailments such as fertility problems in both women and men ...
Mohayabo Malebatja, Sheku Alfred Kanu
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
La prescription de stimulants aux enfants « hyperactifs » : une étude pilote des incitatifs et des contraintes pour les parents, les médecins et les enseignants [PDF]
, 2008 Christine Doré, David Cohen
openalex +1 more source
Effect of Systemic Administration of CD4+ T cells and Local Administration of T-cell Stimulants on T-cell Activity in Psoriatic Skin Xenografts on NOG Mice [PDF]
, 2023 Pernille KF Christensen +5 more
openalex +1 more source
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source