Results 201 to 210 of about 303,496 (386)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Stimulant Treatment Gap in ADHD Patients with Heroin Use Disorder: Clinical and Behavioural Consequences. [PDF]

Int J Environ Res Public Health
Pallucchini A, Varese M, Pergentini I, Gemignani S, Parapetto E, Maremmani I, Maremmani AGI.   +6 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Nutrition for Youth Athletes with ADHD: What We Know and Practical Applications. [PDF]

Nutrients
Becker TB, Gibbs RL.
europepmc   +1 more source

STUDY OF THE EFFECT OF SPRAYING WITH GROWTH STIMULANTS ROOTEX AND VAGE AMINO IN IMPROVING THE QUALITATIVE CHARACTERISTICS OF THE FRUITS OF ZIZIPHUS SPINA L. TREES

OLA AHMED NAJM, MAHMOUD S. ABDUL-WAHID
openalex   +2 more sources

Cognitive Function as a Transdiagnostic Treatment Target in Stimulant Use Disorders

Journal of dual diagnosis, 2016
M. Sofuoglu, E. DeVito, A. Waters, K. Carroll   +3 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Stimulant medications affect arousal and reward, not attention networks. [PDF]

Cell
Kay BP, Wheelock MD, Siegel JS, Raut RV, Chauvin RJ, Metoki A, Rajesh A, Eck A, Pollaro J, Wang A, Suljic V, Adeyemo B, Baden NJ, Scheidter KM, Monk JS, Whiting FI, Ramirez-Perez N, Krimmel SR, Shinohara RT, Tervo-Clemmens B, Hermosillo RJM, Nelson SM, Hendrickson TJ, Madison T, Moore LA, Miranda-Domínguez Ó, Randolph A, Feczko E, Roland JL, Nicol GE, Laumann TO, Marek S, Gordon EM, Raichle ME, Barch DM, Fair DA, Dosenbach NUF.   +36 more
europepmc   +1 more source

Enhancement of Seed Yield Productivity of Squash Plants Using Plant Growth Stimulants.

openalex   +1 more source

Interoceptive attention in opioid and stimulant use disorder

, 2019
Jennifer L. Stewart, Sahib S. Khalsa, Rayus Kuplicki, Maria Puhl, T Investigators, Martin P. Paulus   +5 more
openalex   +2 more sources